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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN9A
All Species:
19.7
Human Site:
S503
Identified Species:
43.33
UniProt:
Q15858
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15858
NP_002968.1
1988
226342
S503
D
A
E
K
L
S
K
S
E
S
E
D
S
I
R
Chimpanzee
Pan troglodytes
XP_001153408
2016
229162
S526
K
N
D
R
V
R
K
S
E
S
E
D
S
I
R
Rhesus Macaque
Macaca mulatta
XP_001101662
1975
225419
R495
A
K
E
R
R
N
R
R
K
K
K
N
Q
K
K
Dog
Lupus familis
XP_545503
1986
226048
S502
D
N
E
K
L
S
K
S
E
S
E
E
S
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62205
1984
225794
S502
D
D
E
K
L
S
K
S
G
S
E
E
S
I
R
Rat
Rattus norvegicus
O08562
1984
226021
S502
D
D
E
K
L
S
K
S
G
S
E
E
S
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513667
1993
226281
S508
D
D
E
K
L
P
K
S
E
S
E
E
S
I
R
Chicken
Gallus gallus
XP_001233892
2006
228268
G516
K
Q
K
E
Q
A
E
G
E
K
D
E
E
E
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
R437
D
K
E
E
E
F
Q
R
L
L
E
Q
L
K
N
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
C498
N
N
E
A
L
K
D
C
N
G
R
P
I
P
R
Fruit Fly
Dros. melanogaster
P35500
2131
239344
K518
N
D
D
N
N
K
E
K
M
S
I
R
S
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
97
94.4
N.A.
93.2
93
N.A.
84.1
79.1
N.A.
60.5
60.5
43.4
N.A.
N.A.
N.A.
Protein Similarity:
100
87
98.1
97.3
N.A.
96.3
96.4
N.A.
91.1
87.4
N.A.
73.5
73.6
61.7
N.A.
N.A.
N.A.
P-Site Identity:
100
60
6.6
86.6
N.A.
80
80
N.A.
80
6.6
N.A.
20
20
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
53.3
93.3
N.A.
86.6
86.6
N.A.
86.6
46.6
N.A.
33.3
26.6
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
55
37
19
0
0
0
10
0
0
0
10
19
0
0
0
% D
% Glu:
0
0
73
19
10
0
19
0
46
0
64
46
10
10
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
19
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
10
55
0
% I
% Lys:
19
19
10
46
0
19
55
10
10
19
10
0
0
19
10
% K
% Leu:
0
0
0
0
55
0
0
0
10
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
19
28
0
10
10
10
0
0
10
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
10
0
0
10
0
10
0
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
19
10
10
10
19
0
0
10
10
0
0
64
% R
% Ser:
0
0
0
0
0
37
0
55
0
64
0
0
64
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _