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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCN9A All Species: 30.91
Human Site: Y63 Identified Species: 68
UniProt: Q15858 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15858 NP_002968.1 1988 226342 Y63 G K Q L P F I Y G D I P P G M
Chimpanzee Pan troglodytes XP_001153408 2016 229162 Y66 G K S L P F I Y G D I P P E M
Rhesus Macaque Macaca mulatta XP_001101662 1975 225419 Y61 G K Q L P F I Y G D I P P G M
Dog Lupus familis XP_545503 1986 226048 Y63 G K Q L P F I Y G D I P P G M
Cat Felis silvestris
Mouse Mus musculus Q62205 1984 225794 Y63 G K Q L P F I Y G D I P P G M
Rat Rattus norvegicus O08562 1984 226021 Y63 G K Q L P F I Y G D I P P G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513667 1993 226281 Y64 G K Q L P F I Y G D I P P G M
Chicken Gallus gallus XP_001233892 2006 228268 Y66 G K T L P F I Y G D I P P G M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 E36 Q E K S T R E E L E G A E E E
Tiger Blowfish Takifugu rubipres Q2XVR7 1892 213080 F62 G K S L P M I F G D P P S E L
Fruit Fly Dros. melanogaster P35500 2131 239344 Q90 V P I P V R L Q G S F P P E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78 97 94.4 N.A. 93.2 93 N.A. 84.1 79.1 N.A. 60.5 60.5 43.4 N.A. N.A. N.A.
Protein Similarity: 100 87 98.1 97.3 N.A. 96.3 96.4 N.A. 91.1 87.4 N.A. 73.5 73.6 61.7 N.A. N.A. N.A.
P-Site Identity: 100 86.6 100 100 N.A. 100 100 N.A. 100 93.3 N.A. 0 53.3 20 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. 100 93.3 N.A. 20 66.6 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 10 10 0 10 0 0 10 37 10 % E
% Phe: 0 0 0 0 0 73 0 10 0 0 10 0 0 0 0 % F
% Gly: 82 0 0 0 0 0 0 0 91 0 10 0 0 64 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 82 0 0 0 73 0 0 0 0 % I
% Lys: 0 82 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 82 0 0 10 0 10 0 0 0 0 0 19 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 73 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 10 82 0 0 0 0 0 10 91 82 0 0 % P
% Gln: 10 0 55 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 19 10 0 0 0 0 0 10 0 0 10 0 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _