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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
13.03
Human Site:
S1975
Identified Species:
28.67
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S1975
P
E
V
S
E
L
K
S
V
Q
P
S
N
H
G
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2400
A
P
H
E
A
R
P
P
L
E
R
G
H
S
T
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S1972
P
E
V
S
E
L
K
S
V
Q
P
S
N
H
G
Dog
Lupus familis
XP_547425
2465
277756
S2117
P
E
V
S
E
L
K
S
V
Q
S
S
N
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
R1935
P
V
S
G
L
S
G
R
S
G
Y
P
S
M
S
Rat
Rattus norvegicus
Q07652
2222
252098
R1884
P
V
S
G
L
S
G
R
S
G
Y
P
S
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
R1857
P
T
I
C
R
E
E
R
D
I
R
D
Y
C
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
T1500
I
C
L
F
E
I
T
T
S
A
G
W
D
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
S1522
S
R
H
P
S
Q
E
S
L
T
G
A
D
A
G
Honey Bee
Apis mellifera
NP_001159376
1904
215872
I1575
N
E
E
L
R
D
T
I
R
S
I
W
P
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
S1637
G
R
D
P
D
R
E
S
R
H
H
R
Y
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
0
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
13.3
13.3
N.A.
N.A.
20
N.A.
33.3
N.A.
40
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
10
0
10
0
10
0
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
10
10
0
0
10
0
0
10
19
0
0
% D
% Glu:
0
37
10
10
37
10
28
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
19
0
0
19
0
0
19
19
10
0
10
37
% G
% His:
0
0
19
0
0
0
0
0
0
10
10
0
10
28
0
% H
% Ile:
10
0
10
0
0
10
0
10
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
19
28
0
0
19
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
28
0
10
% N
% Pro:
55
10
0
19
0
0
10
10
0
0
19
19
10
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
28
0
0
0
0
10
% Q
% Arg:
0
19
0
0
19
19
0
28
19
0
19
10
0
10
0
% R
% Ser:
10
0
19
28
10
19
0
46
28
10
10
28
19
10
19
% S
% Thr:
0
10
0
0
0
0
19
10
0
10
0
0
0
0
10
% T
% Val:
0
19
28
0
0
0
0
0
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
19
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _