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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
4.24
Human Site:
S2181
Identified Species:
9.33
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2181
S
L
I
R
H
A
G
S
I
S
P
P
A
D
G
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
G2630
G
A
S
T
P
G
R
G
G
R
R
Q
L
P
Q
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2178
S
L
I
R
H
V
G
S
I
S
P
P
A
D
G
Dog
Lupus familis
XP_547425
2465
277756
R2333
P
P
A
D
G
S
E
R
G
S
P
L
T
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
G2141
S
L
M
R
H
T
G
G
I
S
P
P
P
D
G
Rat
Rattus norvegicus
Q07652
2222
252098
G2090
S
L
M
R
H
T
G
G
I
S
P
P
P
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
R2063
D
D
P
D
I
S
Y
R
T
F
T
P
A
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
R1705
I
A
V
Q
R
I
Y
R
R
H
L
L
K
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
H1727
H
T
H
H
S
T
P
H
S
V
H
S
L
P
H
Honey Bee
Apis mellifera
NP_001159376
1904
215872
H1780
T
H
Q
H
Y
H
R
H
H
P
H
Q
H
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
Q1842
G
G
S
V
T
P
R
Q
R
Q
R
P
T
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
0
93.3
13.3
N.A.
73.3
73.3
N.A.
N.A.
13.3
N.A.
0
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
0
93.3
20
N.A.
80
80
N.A.
N.A.
26.6
N.A.
13.3
N.A.
0
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
0
10
0
0
0
0
0
0
28
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
19
0
0
0
0
0
0
0
0
0
37
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
19
10
0
0
10
10
37
28
19
0
0
0
0
0
37
% G
% His:
10
10
10
19
37
10
0
19
10
10
19
0
10
0
10
% H
% Ile:
10
0
19
0
10
10
0
0
37
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
37
0
0
0
0
0
0
0
0
10
19
19
0
10
% L
% Met:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
10
10
10
0
10
10
10
0
0
10
46
55
19
28
10
% P
% Gln:
0
0
10
10
0
0
0
10
0
10
0
19
0
0
19
% Q
% Arg:
0
0
0
37
10
0
28
28
19
10
19
0
0
10
0
% R
% Ser:
37
0
19
0
10
19
0
19
10
46
0
10
0
10
0
% S
% Thr:
10
10
0
10
10
28
0
0
10
0
10
0
19
0
0
% T
% Val:
0
0
10
10
0
10
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
19
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _