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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1E All Species: 13.64
Human Site: S933 Identified Species: 30
UniProt: Q15878 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15878 NP_000712.2 2313 261731 S933 V R T E G K E S S S A S R S R
Chimpanzee Pan troglodytes XP_520396 2784 310342 E1378 G S P E E A A E R E P R R H R
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 S930 V R T E G K E S S S A S R S R
Dog Lupus familis XP_547425 2465 277756 L1074 V R T E G K E L S S T S R S R
Cat Felis silvestris
Mouse Mus musculus Q61290 2272 257217 S934 V R T E G K D S A S A S R S R
Rat Rattus norvegicus Q07652 2222 252098 S884 V R T E G K E S A S A S R S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 C843 D K D P Y P P C D V P V G E D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 G540 V L T A T M E G L E D A Q R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 N562 N L V I S L L N S M R S I I S
Honey Bee Apis mellifera NP_001159376 1904 215872 M615 L A L F M L E M F I K V Y A L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 P675 G S P N P D N P S I S S L A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.8 95.8 90.7 N.A. 94.6 92.5 N.A. N.A. 26.4 N.A. 20.4 N.A. 43.5 46.2 N.A. 39.5
Protein Similarity: 100 57.8 96.3 92 N.A. 95.8 93.8 N.A. N.A. 41.9 N.A. 37.4 N.A. 55.8 57.8 N.A. 52.5
P-Site Identity: 100 20 100 86.6 N.A. 86.6 93.3 N.A. N.A. 0 N.A. 20 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 20 100 86.6 N.A. 100 100 N.A. N.A. 6.6 N.A. 33.3 N.A. 20 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 10 10 0 19 0 37 10 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 10 10 0 10 0 10 0 0 0 10 % D
% Glu: 0 0 0 55 10 0 55 10 0 19 0 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 19 0 0 0 46 0 0 10 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 19 0 0 10 10 0 % I
% Lys: 0 10 0 0 0 46 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 19 10 0 0 19 10 10 10 0 0 0 10 0 10 % L
% Met: 0 0 0 0 10 10 0 10 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 10 10 0 0 0 0 0 0 10 % N
% Pro: 0 0 19 10 10 10 10 10 0 0 19 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 46 0 0 0 0 0 0 10 0 10 10 55 10 55 % R
% Ser: 0 19 0 0 10 0 0 37 46 46 10 64 0 46 10 % S
% Thr: 0 0 55 0 10 0 0 0 0 0 10 0 0 0 0 % T
% Val: 55 0 10 0 0 0 0 0 0 10 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _