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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
22.12
Human Site:
Y1217
Identified Species:
48.67
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
Y1217
L
I
L
Q
D
G
S
Y
F
R
D
L
W
N
I
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1658
L
L
L
H
P
G
A
Y
F
R
D
L
W
N
I
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
Y1214
L
I
L
Q
D
G
S
Y
F
R
D
L
W
N
I
Dog
Lupus familis
XP_547425
2465
277756
Y1359
L
I
L
Q
D
G
S
Y
F
R
D
L
W
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
Y1220
L
I
L
Q
D
G
S
Y
F
R
D
L
W
N
I
Rat
Rattus norvegicus
Q07652
2222
252098
Y1169
L
I
L
Q
D
G
S
Y
F
R
D
L
W
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
A1111
N
F
D
N
V
L
S
A
M
M
A
L
F
T
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
L802
L
V
V
L
N
L
F
L
A
L
L
L
S
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
L824
M
L
L
K
I
V
D
L
G
V
I
L
H
P
G
Honey Bee
Apis mellifera
NP_001159376
1904
215872
M877
P
M
L
P
Y
S
S
M
F
I
L
S
P
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
I937
K
N
V
T
N
I
A
I
V
Y
L
L
F
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
13.3
N.A.
13.3
20
N.A.
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
40
N.A.
33.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
10
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
46
0
10
0
0
0
55
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
10
0
64
0
0
0
19
0
19
% F
% Gly:
0
0
0
0
0
55
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
46
0
0
10
10
0
10
0
10
10
0
0
0
55
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
19
73
10
0
19
0
19
0
10
28
91
0
0
0
% L
% Met:
10
10
0
0
0
0
0
10
10
10
0
0
0
10
0
% M
% Asn:
10
10
0
10
19
0
0
0
0
0
0
0
0
55
10
% N
% Pro:
10
0
0
10
10
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
46
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
64
0
0
0
0
10
10
10
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
19
0
% T
% Val:
0
10
19
0
10
10
0
0
10
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% W
% Tyr:
0
0
0
0
10
0
0
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _