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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM189A2 All Species: 25.76
Human Site: S440 Identified Species: 70.83
UniProt: Q15884 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15884 NP_001121080.1 450 49703 S440 V E A E R P H S L I G V I R E
Chimpanzee Pan troglodytes XP_520063 554 60120 S544 V E A E R P H S L I G V I R E
Rhesus Macaque Macaca mulatta XP_001089570 503 55302 S493 V E A E R P H S L I G V I R E
Dog Lupus familis XP_851286 494 54324 S484 V E A E R P H S L I G V I R E
Cat Felis silvestris
Mouse Mus musculus Q4FZH1 290 32190 L281 E A E R P H S L I G V I R E T
Rat Rattus norvegicus XP_001078764 595 64008 S585 A E A E R P H S L I G V I R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516227 448 49517 S438 T E P E R P H S L I G V V R E
Chicken Gallus gallus XP_424828 447 49423 S437 T E H E R P H S L I G V V R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001082828 162 17909 Y153 P S Y F S T F Y S Y T P R L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 85.6 79.9 N.A. 52.8 66.2 N.A. 80.2 71.7 N.A. 23.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 80.6 87 83 N.A. 55.5 69.2 N.A. 85.1 80 N.A. 29.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 0 93.3 N.A. 80 80 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 93.3 N.A. 86.6 86.6 N.A. 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 56 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 78 12 78 0 0 0 0 0 0 0 0 0 12 78 % E
% Phe: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 78 0 0 0 0 % G
% His: 0 0 12 0 0 12 78 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 78 0 12 56 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 12 78 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 0 12 0 12 78 0 0 0 0 0 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 78 0 0 0 0 0 0 0 23 78 0 % R
% Ser: 0 12 0 0 12 0 12 78 12 0 0 0 0 0 0 % S
% Thr: 23 0 0 0 0 12 0 0 0 0 12 0 0 0 12 % T
% Val: 45 0 0 0 0 0 0 0 0 0 12 78 23 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 12 0 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _