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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS72
All Species:
19.7
Human Site:
S127
Identified Species:
33.33
UniProt:
Q15906
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15906
NP_005988.1
364
40594
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Chimpanzee
Pan troglodytes
XP_001166408
349
38648
E123
S
M
R
Q
S
T
A
E
H
T
R
Q
T
F
L
Rhesus Macaque
Macaca mulatta
XP_001104866
364
40536
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Dog
Lupus familis
XP_533052
364
40562
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62481
368
40765
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Rat
Rattus norvegicus
NP_001101165
364
40519
S127
L
E
L
Q
D
D
G
S
D
S
R
K
S
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521676
120
12950
Chicken
Gallus gallus
XP_423393
365
41113
D127
E
L
Q
D
E
V
A
D
S
R
K
H
M
R
Q
Frog
Xenopus laevis
Q6GNJ8
353
40682
V126
Q
E
P
P
D
D
T
V
D
S
R
K
Q
M
R
Zebra Danio
Brachydanio rerio
XP_001335411
351
39846
L126
T
R
L
T
Y
L
R
L
Q
E
R
Q
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM6
351
40423
G129
R
F
T
V
L
D
S
G
R
K
S
I
R
T
S
Honey Bee
Apis mellifera
XP_001120393
301
35528
S93
Y
K
E
P
K
V
Q
S
Q
L
P
S
K
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780191
361
41087
S142
D
S
S
V
R
K
S
S
R
R
S
T
I
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130168
360
40969
I144
E
L
E
A
E
K
A
I
R
K
S
S
R
T
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
99.1
98
N.A.
95.9
96.6
N.A.
26.1
70.6
62.6
56.8
N.A.
38.4
31.5
N.A.
41.2
Protein Similarity:
100
90.6
99.4
98.9
N.A.
96.7
97.8
N.A.
27.2
83.2
75.5
68.4
N.A.
52.7
49.1
N.A.
59.6
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
0
0
60
13.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
0
20
60
20
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
26.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
42.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
22
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
43
50
0
8
43
0
0
0
0
0
0
% D
% Glu:
15
43
15
0
15
0
0
8
0
8
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
36
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% I
% Lys:
0
8
0
0
8
15
0
0
0
15
8
43
8
0
8
% K
% Leu:
36
15
43
0
8
8
0
8
0
8
0
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
43
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
15
0
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
8
0
8
43
0
0
8
0
15
0
0
15
8
8
8
% Q
% Arg:
8
8
8
0
8
0
8
0
22
15
58
0
15
8
50
% R
% Ser:
8
8
8
0
8
0
15
50
8
43
22
15
36
0
15
% S
% Thr:
8
0
8
8
0
8
8
0
0
8
0
8
8
15
0
% T
% Val:
0
0
0
15
0
15
0
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _