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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS72
All Species:
22.12
Human Site:
S352
Identified Species:
37.44
UniProt:
Q15906
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15906
NP_005988.1
364
40594
S352
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Chimpanzee
Pan troglodytes
XP_001166408
349
38648
S337
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Rhesus Macaque
Macaca mulatta
XP_001104866
364
40536
S352
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Dog
Lupus familis
XP_533052
364
40562
S352
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q62481
368
40765
S356
P
P
E
P
L
P
G
S
G
P
R
A
L
R
Q
Rat
Rattus norvegicus
NP_001101165
364
40519
A352
P
P
E
P
L
P
G
A
G
P
R
A
L
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521676
120
12950
L113
G
C
P
G
R
A
R
L
G
R
E
S
R
G
G
Chicken
Gallus gallus
XP_423393
365
41113
S348
A
P
P
G
P
D
P
S
L
R
A
T
R
Q
K
Frog
Xenopus laevis
Q6GNJ8
353
40682
T340
A
D
A
A
Q
R
N
T
R
Q
K
I
I
I
K
Zebra Danio
Brachydanio rerio
XP_001335411
351
39846
S340
P
A
D
T
T
A
K
S
L
K
Q
K
I
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM6
351
40423
N337
W
R
K
L
V
K
E
N
R
L
K
A
S
A
A
Honey Bee
Apis mellifera
XP_001120393
301
35528
P294
R
N
T
V
R
L
E
P
A
S
A
S
M
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780191
361
41087
K351
E
T
K
H
R
K
S
K
G
S
T
S
S
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130168
360
40969
P352
G
G
R
T
W
R
I
P
A
F
D
M
V
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.7
99.1
98
N.A.
95.9
96.6
N.A.
26.1
70.6
62.6
56.8
N.A.
38.4
31.5
N.A.
41.2
Protein Similarity:
100
90.6
99.4
98.9
N.A.
96.7
97.8
N.A.
27.2
83.2
75.5
68.4
N.A.
52.7
49.1
N.A.
59.6
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
13.3
0
13.3
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
26.6
26.6
33.3
N.A.
33.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
26.9
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
42.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
8
0
15
0
8
15
0
15
50
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
0
0
0
0
8
0
0
8
0
% D
% Glu:
8
0
43
0
0
0
15
0
0
0
8
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
15
8
0
15
0
0
43
0
58
0
0
0
0
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
8
15
15
8
% I
% Lys:
0
0
15
0
0
15
8
8
0
8
15
8
0
8
15
% K
% Leu:
0
0
0
8
43
8
0
8
15
8
0
0
43
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
50
50
15
43
8
43
8
15
0
43
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
8
0
0
8
43
% Q
% Arg:
8
8
8
0
22
15
8
0
15
15
43
0
15
43
0
% R
% Ser:
0
0
0
0
0
0
8
50
0
15
0
22
15
0
0
% S
% Thr:
0
8
8
15
8
0
0
8
0
0
8
8
0
0
8
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _