Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS72 All Species: 27.88
Human Site: S71 Identified Species: 47.18
UniProt: Q15906 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15906 NP_005988.1 364 40594 S71 D E G D E P S S D G E A E E P
Chimpanzee Pan troglodytes XP_001166408 349 38648 K71 R K R R V V T K A Y K E P L K
Rhesus Macaque Macaca mulatta XP_001104866 364 40536 S71 D E G D E P S S D G E A E E P
Dog Lupus familis XP_533052 364 40562 S71 D E G D E P S S D G E A E E P
Cat Felis silvestris
Mouse Mus musculus Q62481 368 40765 S71 D E G D E P S S D G E A E E P
Rat Rattus norvegicus NP_001101165 364 40519 S71 D E G D E P S S D G E A E E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521676 120 12950
Chicken Gallus gallus XP_423393 365 41113 S71 D E G E E P T S D Q D E S E P
Frog Xenopus laevis Q6GNJ8 353 40682 S71 D E G D E P T S D H E E D E P
Zebra Danio Brachydanio rerio XP_001335411 351 39846 K74 P V K V V R Q K P K Q R K L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM6 351 40423 E71 D E P V S D Q E E A P E K K R
Honey Bee Apis mellifera XP_001120393 301 35528 D41 G F D E V E Q D H D Y M E E D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780191 361 41087 S71 P E D D E P I S G S D D E G T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130168 360 40969 P78 E S E T D D E P E K E V R E R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 99.1 98 N.A. 95.9 96.6 N.A. 26.1 70.6 62.6 56.8 N.A. 38.4 31.5 N.A. 41.2
Protein Similarity: 100 90.6 99.4 98.9 N.A. 96.7 97.8 N.A. 27.2 83.2 75.5 68.4 N.A. 52.7 49.1 N.A. 59.6
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 60 73.3 0 N.A. 13.3 13.3 N.A. 40
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 0 80 86.6 13.3 N.A. 33.3 20 N.A. 46.6
Percent
Protein Identity: N.A. 26.9 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 42.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 8 0 36 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 58 0 15 50 8 15 0 8 50 8 15 8 8 0 8 % D
% Glu: 8 65 8 15 58 8 8 8 15 0 50 29 50 65 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 50 0 0 0 0 0 8 36 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 15 0 15 8 0 15 8 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 8 0 0 58 0 8 8 0 8 0 8 0 50 % P
% Gln: 0 0 0 0 0 0 22 0 0 8 8 0 0 0 0 % Q
% Arg: 8 0 8 8 0 8 0 0 0 0 0 8 8 0 15 % R
% Ser: 0 8 0 0 8 0 36 58 0 8 0 0 8 0 0 % S
% Thr: 0 0 0 8 0 0 22 0 0 0 0 0 0 0 8 % T
% Val: 0 8 0 15 22 8 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _