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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS72 All Species: 17.27
Human Site: T247 Identified Species: 29.23
UniProt: Q15906 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15906 NP_005988.1 364 40594 T247 A P S V S A L T P H A G T G P
Chimpanzee Pan troglodytes XP_001166408 349 38648 T232 A P S A S A L T P H A G T G P
Rhesus Macaque Macaca mulatta XP_001104866 364 40536 T247 A P S A S A L T P H A G T G P
Dog Lupus familis XP_533052 364 40562 T247 T P T A S A L T P H A G T G P
Cat Felis silvestris
Mouse Mus musculus Q62481 368 40765 G251 S A L A P H A G T G T G A A A
Rat Rattus norvegicus NP_001101165 364 40519 T247 A P T S S A L T A H A G T G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521676 120 12950 R15 P A G R K S M R Q S T A E H T
Chicken Gallus gallus XP_423393 365 41113 A243 L D Q D P Q Q A D A A P A A A
Frog Xenopus laevis Q6GNJ8 353 40682 G235 E E N V D V E G L D H E Q T D
Zebra Danio Brachydanio rerio XP_001335411 351 39846 P240 E S T L S A A P G V P F T N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM6 351 40423 P233 K P T R G A N P A V D S K D L
Honey Bee Apis mellifera XP_001120393 301 35528 P196 I R K A Q T G P M I R Y Q S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780191 361 41087 S253 N V E K V E Q S Q S G S T H P
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130168 360 40969 C254 A S F G S E L C T T S S P Y P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 99.1 98 N.A. 95.9 96.6 N.A. 26.1 70.6 62.6 56.8 N.A. 38.4 31.5 N.A. 41.2
Protein Similarity: 100 90.6 99.4 98.9 N.A. 96.7 97.8 N.A. 27.2 83.2 75.5 68.4 N.A. 52.7 49.1 N.A. 59.6
P-Site Identity: 100 93.3 93.3 80 N.A. 6.6 80 N.A. 0 6.6 6.6 20 N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 13.3 86.6 N.A. 13.3 6.6 13.3 33.3 N.A. 20 0 N.A. 20
Percent
Protein Identity: N.A. 26.9 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 42.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 26.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 15 0 36 0 50 15 8 15 8 43 8 15 15 15 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 8 0 0 0 8 8 8 0 0 8 8 % D
% Glu: 15 8 8 0 0 15 8 0 0 0 0 8 8 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 8 8 8 0 8 15 8 8 8 43 0 36 0 % G
% His: 0 0 0 0 0 8 0 0 0 36 8 0 0 15 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 0 8 8 8 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 0 8 8 0 0 43 0 8 0 0 0 0 0 15 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % N
% Pro: 8 43 0 0 15 0 0 22 29 0 8 8 8 0 50 % P
% Gln: 0 0 8 0 8 8 15 0 15 0 0 0 15 0 0 % Q
% Arg: 0 8 0 15 0 0 0 8 0 0 8 0 0 0 0 % R
% Ser: 8 15 22 8 50 8 0 8 0 15 8 22 0 8 0 % S
% Thr: 8 0 29 0 0 8 0 36 15 8 15 0 50 8 15 % T
% Val: 0 8 0 15 8 8 0 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _