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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS72 All Species: 36.36
Human Site: Y323 Identified Species: 61.54
UniProt: Q15906 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15906 NP_005988.1 364 40594 Y323 F K I I R E A Y K K Y I T A H
Chimpanzee Pan troglodytes XP_001166408 349 38648 Y308 F K I I R E A Y K K Y I T A H
Rhesus Macaque Macaca mulatta XP_001104866 364 40536 Y323 F K I I R E A Y K K Y I T A H
Dog Lupus familis XP_533052 364 40562 Y323 F K I I R E A Y K K Y I T A H
Cat Felis silvestris
Mouse Mus musculus Q62481 368 40765 Y327 F K I I R E A Y K K Y I T A H
Rat Rattus norvegicus NP_001101165 364 40519 Y323 F K I I R E A Y K K Y I T A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521676 120 12950 A84 P A G R P G A A A G R R V T P
Chicken Gallus gallus XP_423393 365 41113 Y319 F K I I R E A Y K K Y I T A H
Frog Xenopus laevis Q6GNJ8 353 40682 Y311 F K I I R D A Y K K Y I T T H
Zebra Danio Brachydanio rerio XP_001335411 351 39846 I311 A N V Q A F R I I R E A Y K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM6 351 40423 Y308 F K I L R E A Y Y M Q L E Q Q
Honey Bee Apis mellifera XP_001120393 301 35528 S265 R T D V N D T S Q S P D L L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780191 361 41087 T322 V T G I A F A T K Q A F K I I
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130168 360 40969 H323 F E S I T G G H L M P K K R R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 99.1 98 N.A. 95.9 96.6 N.A. 26.1 70.6 62.6 56.8 N.A. 38.4 31.5 N.A. 41.2
Protein Similarity: 100 90.6 99.4 98.9 N.A. 96.7 97.8 N.A. 27.2 83.2 75.5 68.4 N.A. 52.7 49.1 N.A. 59.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 86.6 0 N.A. 46.6 0 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 93.3 13.3 N.A. 60 20 N.A. 26.6
Percent
Protein Identity: N.A. 26.9 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 42.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 15 0 79 8 8 0 8 8 0 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 15 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 8 0 0 0 58 0 0 0 0 8 0 8 0 0 % E
% Phe: 72 0 0 0 0 15 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 15 0 0 15 8 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 58 % H
% Ile: 0 0 65 72 0 0 0 8 8 0 0 58 0 8 8 % I
% Lys: 0 65 0 0 0 0 0 0 65 58 0 8 15 8 8 % K
% Leu: 0 0 0 8 0 0 0 0 8 0 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 8 0 0 0 0 0 15 0 0 0 8 % P
% Gln: 0 0 0 8 0 0 0 0 8 8 8 0 0 8 8 % Q
% Arg: 8 0 0 8 65 0 8 0 0 8 8 8 0 8 15 % R
% Ser: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % S
% Thr: 0 15 0 0 8 0 8 8 0 0 0 0 58 15 0 % T
% Val: 8 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 8 0 58 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _