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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZIC1 All Species: 30.61
Human Site: S183 Identified Species: 74.81
UniProt: Q15915 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15915 NP_003403.2 447 48309 S183 E Q Y G Q V T S P R S E H Y A
Chimpanzee Pan troglodytes XP_516806 404 43927 V159 H G Y G P M N V N M A A H H G
Rhesus Macaque Macaca mulatta XP_001093759 1092 112511 S761 E Q Y R Q V A S P R T D P Y S
Dog Lupus familis XP_542652 472 50656 S199 E Q Y R Q V A S P R T D P Y S
Cat Felis silvestris
Mouse Mus musculus P46684 447 48397 S183 E Q Y G Q V T S P R S E H Y A
Rat Rattus norvegicus NP_073168 447 48312 S183 E Q Y G Q V T S P R S E H Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989585 444 48146 S180 E Q Y G Q V T S P R S E H Y A
Frog Xenopus laevis O73689 443 48234 S179 D Q Y G Q V T S P R S E H Y A
Zebra Danio Brachydanio rerio NP_571008 442 48369 S178 E Q Y G H V A S P R S E H Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P39768 609 66219 T164 N H H G N F P T A A V H H P V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 32.5 63.7 N.A. 99.1 99.3 N.A. N.A. 93.5 91.7 88.5 N.A. 36.1 N.A. N.A. N.A.
Protein Similarity: 100 90.3 36.3 70.7 N.A. 99.5 99.7 N.A. N.A. 95.9 95.3 93.2 N.A. 45.6 N.A. N.A. N.A.
P-Site Identity: 100 20 60 60 N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 80 80 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 30 0 10 10 10 10 0 0 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % D
% Glu: 70 0 0 0 0 0 0 0 0 0 0 60 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 80 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 10 10 10 0 10 0 0 0 0 0 0 10 80 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 10 0 80 0 0 0 20 10 0 % P
% Gln: 0 80 0 0 70 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 20 0 0 0 0 0 80 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 80 0 0 60 0 0 0 20 % S
% Thr: 0 0 0 0 0 0 50 10 0 0 20 0 0 0 0 % T
% Val: 0 0 0 0 0 80 0 10 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 90 0 0 0 0 0 0 0 0 0 0 80 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _