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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZIC1
All Species:
32.73
Human Site:
S391
Identified Species:
80
UniProt:
Q15915
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15915
NP_003403.2
447
48309
S391
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Chimpanzee
Pan troglodytes
XP_516806
404
43927
S348
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001093759
1092
112511
S984
H
E
S
S
P
Q
G
S
E
S
S
P
A
A
S
Dog
Lupus familis
XP_542652
472
50656
R417
H
M
K
V
P
P
G
R
P
G
G
V
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
P46684
447
48397
S391
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Rat
Rattus norvegicus
NP_073168
447
48312
S391
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989585
444
48146
S388
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Frog
Xenopus laevis
O73689
443
48234
S387
H
E
A
S
S
Q
G
S
Q
P
S
P
A
A
S
Zebra Danio
Brachydanio rerio
NP_571008
442
48369
S386
H
E
S
S
S
Q
G
S
Q
P
S
P
A
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P39768
609
66219
S382
H
G
N
V
D
E
K
S
P
S
H
G
Y
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
32.5
63.7
N.A.
99.1
99.3
N.A.
N.A.
93.5
91.7
88.5
N.A.
36.1
N.A.
N.A.
N.A.
Protein Similarity:
100
90.3
36.3
70.7
N.A.
99.5
99.7
N.A.
N.A.
95.9
95.3
93.2
N.A.
45.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
13.3
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
13.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
80
80
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
80
0
0
0
10
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
90
0
0
10
10
10
0
10
10
% G
% His:
100
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
10
0
0
20
70
0
80
0
0
0
% P
% Gln:
0
0
0
0
0
80
0
0
70
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
70
80
70
0
0
90
0
20
80
0
0
0
90
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
20
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _