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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZIC1 All Species: 17.88
Human Site: T182 Identified Species: 43.7
UniProt: Q15915 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15915 NP_003403.2 447 48309 T182 P E Q Y G Q V T S P R S E H Y
Chimpanzee Pan troglodytes XP_516806 404 43927 N158 L H G Y G P M N V N M A A H H
Rhesus Macaque Macaca mulatta XP_001093759 1092 112511 A760 S E Q Y R Q V A S P R T D P Y
Dog Lupus familis XP_542652 472 50656 A198 S E Q Y R Q V A S P R T D P Y
Cat Felis silvestris
Mouse Mus musculus P46684 447 48397 T182 P E Q Y G Q V T S P R S E H Y
Rat Rattus norvegicus NP_073168 447 48312 T182 P E Q Y G Q V T S P R S E H Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989585 444 48146 T179 A E Q Y G Q V T S P R S E H Y
Frog Xenopus laevis O73689 443 48234 T178 P D Q Y G Q V T S P R S E H Y
Zebra Danio Brachydanio rerio NP_571008 442 48369 A177 A E Q Y G H V A S P R S E H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P39768 609 66219 P163 Y N H H G N F P T A A V H H P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 32.5 63.7 N.A. 99.1 99.3 N.A. N.A. 93.5 91.7 88.5 N.A. 36.1 N.A. N.A. N.A.
Protein Similarity: 100 90.3 36.3 70.7 N.A. 99.5 99.7 N.A. N.A. 95.9 95.3 93.2 N.A. 45.6 N.A. N.A. N.A.
P-Site Identity: 100 20 60 60 N.A. 100 100 N.A. N.A. 93.3 93.3 80 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 40 73.3 73.3 N.A. 100 100 N.A. N.A. 93.3 100 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 0 0 0 30 0 10 10 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 20 0 0 % D
% Glu: 0 70 0 0 0 0 0 0 0 0 0 0 60 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 80 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 10 10 0 10 0 0 0 0 0 0 10 80 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 10 0 10 0 0 0 0 0 % N
% Pro: 40 0 0 0 0 10 0 10 0 80 0 0 0 20 10 % P
% Gln: 0 0 80 0 0 70 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 20 0 0 0 0 0 80 0 0 0 0 % R
% Ser: 20 0 0 0 0 0 0 0 80 0 0 60 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 10 0 0 20 0 0 0 % T
% Val: 0 0 0 0 0 0 80 0 10 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 90 0 0 0 0 0 0 0 0 0 0 80 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _