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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZYX
All Species:
4.55
Human Site:
S281
Identified Species:
10
UniProt:
Q15942
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15942
NP_001010972.1
572
61277
S281
T
P
V
A
S
K
F
S
P
G
A
P
G
G
S
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
G270
P
P
P
S
T
R
G
G
M
D
Y
A
Y
I
P
Rhesus Macaque
Macaca mulatta
XP_001091281
572
61261
S281
T
P
V
A
S
K
F
S
P
G
A
P
G
G
S
Dog
Lupus familis
XP_539852
490
53325
L212
G
S
Q
P
N
Q
K
L
G
S
P
E
V
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62523
564
60772
G280
P
G
A
P
S
G
P
G
P
Q
P
I
K
K
W
Rat
Rattus norvegicus
Q5XI07
632
68242
A280
I
P
P
S
G
Q
Q
A
E
S
G
F
G
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512190
613
66056
G308
Q
D
A
Y
Y
S
G
G
P
G
Y
G
G
K
N
Chicken
Gallus gallus
Q04584
542
58519
M245
K
P
G
A
T
V
P
M
A
P
S
N
S
T
R
Frog
Xenopus laevis
A5H447
663
70707
A323
T
P
A
A
K
H
E
A
P
P
P
T
V
P
S
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
Q333
M
S
A
Y
P
E
L
Q
L
P
M
L
G
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
C176
N
T
I
P
K
G
D
C
A
A
C
G
K
P
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
98.5
72.5
N.A.
86.5
32.2
N.A.
34.2
53.8
41.4
24.3
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
100
46.4
98.9
76.4
N.A.
89.3
47.4
N.A.
48.6
66
53.2
40.4
N.A.
N.A.
N.A.
31.6
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
13.3
13.3
N.A.
20
13.3
33.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
20
N.A.
13.3
40
N.A.
26.6
26.6
40
13.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
37
0
0
0
19
19
10
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
10
0
10
19
19
28
10
28
10
19
46
19
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
10
0
10
10
% I
% Lys:
10
0
0
0
19
19
10
0
0
0
0
0
19
19
0
% K
% Leu:
0
0
0
0
0
0
10
10
10
0
0
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
10
10
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% N
% Pro:
19
55
19
28
10
0
19
0
46
28
28
19
0
37
10
% P
% Gln:
10
0
10
0
0
19
10
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
19
0
19
28
10
0
19
0
19
10
0
10
0
37
% S
% Thr:
28
10
0
0
19
0
0
0
0
0
0
10
0
10
10
% T
% Val:
0
0
19
0
0
10
0
0
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
19
10
0
0
0
0
0
19
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _