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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZYX All Species: 6.67
Human Site: S308 Identified Species: 14.67
UniProt: Q15942 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15942 NP_001010972.1 572 61277 S308 A L S A G T G S P Q P P S F T
Chimpanzee Pan troglodytes XP_001159438 612 65827 Y297 A P N Q G R Y Y E G Y Y A A G
Rhesus Macaque Macaca mulatta XP_001091281 572 61261 S308 A L S A G T G S P Q P P S F T
Dog Lupus familis XP_539852 490 53325 K239 T Y A Q Q K E K P R V Q E K Q
Cat Felis silvestris
Mouse Mus musculus Q62523 564 60772 T307 S P Q P P S F T Y A Q Q K E K
Rat Rattus norvegicus Q5XI07 632 68242 R307 A C P S Y G G R N E A D P A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 P335 K P E P T Y A P P V A P P Q N
Chicken Gallus gallus Q04584 542 58519 R272 S P S G P L S R P Q P P N F T
Frog Xenopus laevis A5H447 663 70707 E350 R E R P R V L E K P R A N L Q
Zebra Danio Brachydanio rerio A8DZE6 648 70883 R360 P N G L H N N R V H L Q T F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09476 413 46434 C203 H P E H Y T C C E C G A E L G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 98.5 72.5 N.A. 86.5 32.2 N.A. 34.2 53.8 41.4 24.3 N.A. N.A. N.A. 21.3 N.A.
Protein Similarity: 100 46.4 98.9 76.4 N.A. 89.3 47.4 N.A. 48.6 66 53.2 40.4 N.A. N.A. N.A. 31.6 N.A.
P-Site Identity: 100 13.3 100 6.6 N.A. 0 13.3 N.A. 13.3 46.6 0 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 100 20 N.A. 20 26.6 N.A. 13.3 60 6.6 13.3 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 10 19 0 0 10 0 0 10 19 19 10 19 0 % A
% Cys: 0 10 0 0 0 0 10 10 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 10 19 0 0 0 10 10 19 10 0 0 19 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 37 0 % F
% Gly: 0 0 10 10 28 10 28 0 0 10 10 0 0 0 19 % G
% His: 10 0 0 10 10 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 0 10 10 0 0 0 10 10 10 % K
% Leu: 0 19 0 10 0 10 10 0 0 0 10 0 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 0 0 10 10 0 10 0 0 0 19 0 10 % N
% Pro: 10 46 10 28 19 0 0 10 46 10 28 37 19 0 10 % P
% Gln: 0 0 10 19 10 0 0 0 0 28 10 28 0 10 19 % Q
% Arg: 10 0 10 0 10 10 0 28 0 10 10 0 0 0 0 % R
% Ser: 19 0 28 10 0 10 10 19 0 0 0 0 19 0 0 % S
% Thr: 10 0 0 0 10 28 0 10 0 0 0 0 10 0 28 % T
% Val: 0 0 0 0 0 10 0 0 10 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 19 10 10 10 10 0 10 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _