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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZYX
All Species:
13.64
Human Site:
S508
Identified Species:
30
UniProt:
Q15942
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15942
NP_001010972.1
572
61277
S508
A
P
R
C
S
V
C
S
E
P
I
M
P
E
P
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
K540
A
P
R
C
S
V
C
K
E
P
I
M
P
A
P
Rhesus Macaque
Macaca mulatta
XP_001091281
572
61261
S508
A
P
R
C
S
V
C
S
E
P
I
M
P
E
P
Dog
Lupus familis
XP_539852
490
53325
E426
A
P
R
C
S
V
C
E
G
P
I
M
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62523
564
60772
S500
A
P
R
C
S
V
C
S
E
P
I
M
P
E
P
Rat
Rattus norvegicus
Q5XI07
632
68242
K560
A
P
R
C
S
V
C
K
E
P
I
M
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512190
613
66056
K541
A
P
R
C
S
V
C
K
E
P
I
M
P
A
P
Chicken
Gallus gallus
Q04584
542
58519
S476
A
P
R
C
S
V
C
S
E
P
I
M
P
E
P
Frog
Xenopus laevis
A5H447
663
70707
G596
A
P
R
C
C
V
C
G
D
P
I
A
P
E
P
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
N568
A
P
K
C
A
S
C
N
Q
P
I
L
P
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
R357
G
S
I
C
S
Q
C
R
G
A
I
N
G
R
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
98.5
72.5
N.A.
86.5
32.2
N.A.
34.2
53.8
41.4
24.3
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
100
46.4
98.9
76.4
N.A.
89.3
47.4
N.A.
48.6
66
53.2
40.4
N.A.
N.A.
N.A.
31.6
N.A.
P-Site Identity:
100
86.6
100
86.6
N.A.
100
86.6
N.A.
86.6
100
73.3
46.6
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
86.6
100
86.6
N.A.
100
86.6
N.A.
86.6
100
80
80
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
91
0
0
0
10
0
0
0
0
10
0
10
0
37
0
% A
% Cys:
0
0
0
100
10
0
100
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
64
0
0
0
0
55
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
19
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
28
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
91
0
0
0
0
0
0
0
91
0
0
91
0
82
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
82
0
0
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
82
10
0
37
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
82
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _