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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
44.24
Human Site:
S543
Identified Species:
69.52
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
S543
H
L
T
L
R
D
D
S
I
P
V
N
R
N
L
Chimpanzee
Pan troglodytes
XP_517508
617
68419
S543
H
L
T
L
R
D
D
S
I
P
V
N
R
N
L
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
S543
H
L
T
L
R
D
D
S
I
P
V
K
R
N
L
Dog
Lupus familis
XP_853781
600
66768
S526
H
L
T
L
R
D
D
S
I
P
V
N
R
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
S542
H
L
T
L
K
D
D
S
I
P
V
N
R
N
L
Rat
Rattus norvegicus
Q6UPE1
616
68180
S542
H
L
T
L
K
D
D
S
I
P
V
N
R
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
S595
H
L
T
L
K
D
D
S
V
P
V
N
K
N
L
Chicken
Gallus gallus
NP_001026705
477
53116
A415
S
G
M
L
A
S
E
A
I
F
N
Q
L
T
N
Frog
Xenopus laevis
NP_001087869
616
68418
S542
H
L
T
L
K
D
D
S
T
P
V
N
R
N
L
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
S543
H
L
T
L
K
D
D
S
I
P
V
S
K
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
R530
H
L
T
L
K
D
D
R
I
P
V
D
H
N
L
Honey Bee
Apis mellifera
XP_624722
606
67014
T532
H
L
T
L
A
D
D
T
V
P
V
K
K
N
L
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
Q522
H
L
T
L
K
N
D
Q
V
P
L
D
V
N
L
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
S539
H
L
T
L
K
D
D
S
V
P
V
N
R
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
H540
V
S
R
T
G
T
Y
H
D
D
D
E
P
C
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
80
13.3
86.6
80
N.A.
73.3
66.6
53.3
86.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
26.6
93.3
100
N.A.
86.6
86.6
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
0
80
87
0
7
7
7
14
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
87
0
0
0
0
0
0
7
0
0
0
0
7
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
54
0
0
0
0
0
0
14
20
0
0
% K
% Leu:
0
87
0
94
0
0
0
0
0
0
7
0
7
0
87
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
54
0
87
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
87
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% Q
% Arg:
0
0
7
0
27
0
0
7
0
0
0
0
54
0
0
% R
% Ser:
7
7
0
0
0
7
0
67
0
0
0
7
0
0
0
% S
% Thr:
0
0
87
7
0
7
0
7
7
0
0
0
0
7
0
% T
% Val:
7
0
0
0
0
0
0
0
27
0
80
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _