Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ETFDH All Species: 22.42
Human Site: S551 Identified Species: 35.24
UniProt: Q16134 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16134 NP_004444.2 617 68495 S551 I P V N R N L S I Y D G P E Q
Chimpanzee Pan troglodytes XP_517508 617 68419 S551 I P V N R N L S I Y D G P E Q
Rhesus Macaque Macaca mulatta XP_001097120 616 68420 S551 I P V K R N L S I Y D G P E Q
Dog Lupus familis XP_853781 600 66768 S534 I P V N R N L S L F D G P E Q
Cat Felis silvestris
Mouse Mus musculus Q921G7 616 68072 S550 I P V N R N L S I Y D G P E Q
Rat Rattus norvegicus Q6UPE1 616 68180 S550 I P V N R N L S I Y D G P E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510390 669 74482 E603 V P V N K N L E I Y D G P E G
Chicken Gallus gallus NP_001026705 477 53116 E423 I F N Q L T N E N L Q S K T I
Frog Xenopus laevis NP_001087869 616 68418 A550 T P V N R N L A I F D G P E Q
Zebra Danio Brachydanio rerio NP_001004598 617 68912 A551 I P V S K N L A I Y D G P E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610536 604 65970 A538 I P V D H N L A L Y E G P E Q
Honey Bee Apis mellifera XP_624722 606 67014 A540 V P V K K N L A I F A G P E G
Nematode Worm Caenorhab. elegans Q11190 597 65317 A530 V P L D V N L A V Y G G P E A
Sea Urchin Strong. purpuratus XP_792035 613 67384 A547 V P V N R N L A I Y D G P E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08822 631 69615 L548 D D D E P C H L R V P G Q D M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 92.2 N.A. 92.3 93.1 N.A. 82 65.4 84.2 80.8 N.A. 65.1 67.7 59.9 70
Protein Similarity: 100 99.6 99 94.6 N.A. 95.7 95.9 N.A. 88.4 70.6 91.9 90.5 N.A. 78.9 80.8 75.6 81.8
P-Site Identity: 100 100 93.3 86.6 N.A. 100 100 N.A. 73.3 6.6 80 80 N.A. 66.6 53.3 46.6 86.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 86.6 6.6 93.3 100 N.A. 93.3 80 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 64.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 40 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 14 0 0 0 0 0 0 67 0 0 7 0 % D
% Glu: 0 0 0 7 0 0 0 14 0 0 7 0 0 87 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 20 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 7 94 0 0 14 % G
% His: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 60 0 0 0 0 0 0 0 67 0 0 0 0 0 7 % I
% Lys: 0 0 0 14 20 0 0 0 0 0 0 0 7 0 0 % K
% Leu: 0 0 7 0 7 0 87 7 14 7 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 54 0 87 7 0 7 0 0 0 0 0 0 % N
% Pro: 0 87 0 0 7 0 0 0 0 0 7 0 87 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 7 0 7 0 67 % Q
% Arg: 0 0 0 0 54 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 40 0 0 0 7 0 0 0 % S
% Thr: 7 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % T
% Val: 27 0 80 0 7 0 0 0 7 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _