Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ETFDH All Species: 46.06
Human Site: T151 Identified Species: 72.38
UniProt: Q16134 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16134 NP_004444.2 617 68495 T151 E D R F G I L T E K Y R I P V
Chimpanzee Pan troglodytes XP_517508 617 68419 T151 E D R F G I L T E K Y R I P V
Rhesus Macaque Macaca mulatta XP_001097120 616 68420 T151 E D R F G I L T E K Y R I P V
Dog Lupus familis XP_853781 600 66768 K132 E E L F P D W K E K G A P L N
Cat Felis silvestris
Mouse Mus musculus Q921G7 616 68072 T150 E D R F A I L T E K H R I P V
Rat Rattus norvegicus Q6UPE1 616 68180 T150 E D R F A I L T E K H R I P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510390 669 74482 T203 E D R F G I L T E K S R I P V
Chicken Gallus gallus NP_001026705 477 53116 T38 H K A G W A S T A T V P R I T
Frog Xenopus laevis NP_001087869 616 68418 T150 E D K F G I L T K K H R I P V
Zebra Danio Brachydanio rerio NP_001004598 617 68912 T151 E D K F S I L T E K Y R I P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610536 604 65970 T140 K D T F S F L T G S G R I S I
Honey Bee Apis mellifera XP_624722 606 67014 T140 E D K F A F L T E K N R L S I
Nematode Worm Caenorhab. elegans Q11190 597 65317 T133 S E S I A I L T E S G R I P V
Sea Urchin Strong. purpuratus XP_792035 613 67384 T142 E D K F S F L T E K H R I P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08822 631 69615 T143 K E L A T L V T K E H L K F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 92.2 N.A. 92.3 93.1 N.A. 82 65.4 84.2 80.8 N.A. 65.1 67.7 59.9 70
Protein Similarity: 100 99.6 99 94.6 N.A. 95.7 95.9 N.A. 88.4 70.6 91.9 90.5 N.A. 78.9 80.8 75.6 81.8
P-Site Identity: 100 100 100 26.6 N.A. 86.6 86.6 N.A. 93.3 6.6 80 86.6 N.A. 40 53.3 53.3 66.6
P-Site Similarity: 100 100 100 33.3 N.A. 93.3 93.3 N.A. 93.3 6.6 100 93.3 N.A. 53.3 73.3 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 64.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 27 7 0 0 7 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 74 0 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 74 20 0 0 0 0 0 0 74 7 0 0 0 0 0 % E
% Phe: 0 0 0 80 0 20 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 7 34 0 0 0 7 0 20 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % H
% Ile: 0 0 0 7 0 60 0 0 0 0 0 0 74 7 20 % I
% Lys: 14 7 27 0 0 0 0 7 14 74 0 0 7 0 0 % K
% Leu: 0 0 14 0 0 7 80 0 0 0 0 7 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 7 7 67 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 40 0 0 0 0 0 0 0 0 80 7 0 0 % R
% Ser: 7 0 7 0 20 0 7 0 0 14 7 0 0 14 0 % S
% Thr: 0 0 7 0 7 0 0 94 0 7 0 0 0 0 7 % T
% Val: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 60 % V
% Trp: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _