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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
46.36
Human Site:
Y172
Identified Species:
72.86
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
Y172
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Chimpanzee
Pan troglodytes
XP_517508
617
68419
Y172
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
Y172
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
V
Dog
Lupus familis
XP_853781
600
66768
R155
G
I
L
T
E
K
Y
R
I
P
V
P
I
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
Y171
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Rat
Rattus norvegicus
Q6UPE1
616
68180
Y171
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
Y224
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
L
Chicken
Gallus gallus
NP_001026705
477
53116
D56
T
I
H
P
R
D
K
D
K
R
W
E
G
V
N
Frog
Xenopus laevis
NP_001087869
616
68418
Y171
P
M
N
N
H
G
N
Y
I
V
R
L
G
H
F
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
Y172
P
M
N
N
H
G
N
Y
L
V
R
L
G
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
Y161
P
M
D
N
H
G
N
Y
V
V
R
L
G
H
L
Honey Bee
Apis mellifera
XP_624722
606
67014
Y161
P
M
Y
N
H
G
N
Y
I
V
R
L
G
H
V
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
Y154
P
L
A
N
H
G
N
Y
I
V
R
L
G
K
V
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
G168
G
N
Y
I
V
R
L
G
N
F
V
R
W
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
Y171
M
I
N
K
G
R
N
Y
I
V
S
L
N
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
93.3
6.6
N.A.
100
100
N.A.
100
6.6
93.3
86.6
N.A.
86.6
86.6
73.3
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
20
93.3
93.3
N.A.
100
93.3
86.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
7
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
14
% F
% Gly:
14
0
0
0
7
74
0
7
0
0
0
0
80
0
7
% G
% His:
0
0
7
0
74
0
0
0
0
0
0
0
0
67
0
% H
% Ile:
0
20
0
7
0
0
0
0
74
0
0
0
7
0
0
% I
% Lys:
0
0
0
7
0
7
7
0
7
0
0
0
0
7
0
% K
% Leu:
0
7
7
0
0
0
7
0
7
0
0
80
0
14
40
% L
% Met:
7
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
60
74
0
0
80
0
7
0
0
0
7
0
7
% N
% Pro:
74
0
0
7
0
0
0
0
0
7
0
7
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
7
14
0
7
0
7
74
7
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% S
% Thr:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
7
80
14
0
0
7
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% W
% Tyr:
0
0
14
0
0
0
7
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _