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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT7 All Species: 10.3
Human Site: Y133 Identified Species: 20.61
UniProt: Q16181 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16181 NP_001011553.2 437 50680 Y133 C W Q P V I D Y I D S K F E D
Chimpanzee Pan troglodytes Q5R1W1 434 50272 F135 I D Y I D S K F E D Y L N A E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532516 396 46160 F138 L K P L D I E F M K R L H E K
Cat Felis silvestris
Mouse Mus musculus O55131 436 50531 I133 W Q P V I D Y I D S K F E D Y
Rat Rattus norvegicus Q9WVC0 436 50489 I133 W Q P V I D Y I D S K F E D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMH1 349 40206 S133 E R Y L H D E S G L N R R H I
Frog Xenopus laevis Q9DE33 356 40909 S133 E R Y L H D E S G L N R R H I
Zebra Danio Brachydanio rerio A4FUM1 423 49080 E133 F E N F L E E E L K I K R S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40797 539 60125 Y226 C W V P I L E Y V D S K Y E E
Honey Bee Apis mellifera XP_001121636 646 72341 Y350 C W V P V I E Y I E S K Y E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175696 462 53661 H165 I E F M K R L H D K V N I I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32457 520 60021 V202 G V K L N L N V I D T E G F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 N.A. 89 N.A. 98.8 98.8 N.A. N.A. 49.2 49.2 41.1 N.A. 54.9 48.4 N.A. 66.2
Protein Similarity: 100 99 N.A. 89.6 N.A. 99 99 N.A. N.A. 64.5 64.7 60.6 N.A. 67.5 57.4 N.A. 77.4
P-Site Identity: 100 6.6 N.A. 13.3 N.A. 0 0 N.A. N.A. 0 0 6.6 N.A. 53.3 66.6 N.A. 0
P-Site Similarity: 100 20 N.A. 33.3 N.A. 13.3 13.3 N.A. N.A. 20 20 26.6 N.A. 93.3 93.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 17 34 9 0 25 34 0 0 0 17 9 % D
% Glu: 17 17 0 0 0 9 50 9 9 9 0 9 17 34 25 % E
% Phe: 9 0 9 9 0 0 0 17 0 0 0 17 9 9 0 % F
% Gly: 9 0 0 0 0 0 0 0 17 0 0 0 9 0 9 % G
% His: 0 0 0 0 17 0 0 9 0 0 0 0 9 17 0 % H
% Ile: 17 0 0 9 25 25 0 17 25 0 9 0 9 9 17 % I
% Lys: 0 9 9 0 9 0 9 0 0 25 17 34 0 0 9 % K
% Leu: 9 0 0 34 9 17 9 0 9 17 0 17 0 0 9 % L
% Met: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 9 0 0 0 17 9 9 0 0 % N
% Pro: 0 0 25 25 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 0 17 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 17 0 0 0 9 0 0 0 0 9 17 25 0 0 % R
% Ser: 0 0 0 0 0 9 0 17 0 17 25 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 9 17 17 17 0 0 9 9 0 9 0 0 0 0 % V
% Trp: 17 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 25 0 0 0 17 25 0 0 9 0 17 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _