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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UAP1
All Species:
32.42
Human Site:
S446
Identified Species:
50.95
UniProt:
Q16222
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16222
NP_003106.3
522
58769
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Chimpanzee
Pan troglodytes
XP_001174283
522
58736
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Rhesus Macaque
Macaca mulatta
XP_001118199
522
58639
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Dog
Lupus familis
XP_849867
522
58787
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91YN5
522
58590
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Rat
Rattus norvegicus
XP_573497
521
58376
S446
H
F
I
D
E
N
G
S
R
L
P
A
I
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509643
385
43006
S332
P
S
D
L
P
L
S
S
S
S
S
S
C
R
I
Chicken
Gallus gallus
XP_415568
501
55961
C444
R
F
L
D
E
D
G
C
R
I
P
E
K
L
S
Frog
Xenopus laevis
NP_001091348
523
58611
T446
H
F
V
D
E
N
G
T
W
I
P
A
I
P
L
Zebra Danio
Brachydanio rerio
Q7ZWD4
505
56395
T450
D
E
Q
N
K
P
F
T
P
K
H
S
T
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609032
520
58196
K466
S
D
L
H
R
L
H
K
K
Y
I
E
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18493
484
53478
V427
C
Q
R
D
L
S
N
V
N
K
L
W
L
E
R
Sea Urchin
Strong. purpuratus
XP_779933
489
55054
T425
N
F
I
D
S
D
G
T
S
I
P
A
I
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64765
502
55741
A442
N
Y
D
T
P
E
S
A
R
L
L
V
L
R
L
Baker's Yeast
Sacchar. cerevisiae
P43123
477
53458
L424
D
N
P
E
T
S
R
L
A
Y
L
K
L
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
96.1
N.A.
93.4
93.3
N.A.
48.4
58.8
73.6
56.7
N.A.
50.3
N.A.
36.4
57.8
Protein Similarity:
100
100
99.2
98.8
N.A.
96.9
96.5
N.A.
61.2
72
85.4
71.8
N.A.
69.7
N.A.
55.3
73.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
40
66.6
0
N.A.
0
N.A.
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
60
86.6
33.3
N.A.
13.3
N.A.
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
7
0
0
54
0
14
0
% A
% Cys:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% C
% Asp:
14
7
14
67
0
14
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
7
54
7
0
0
0
0
0
14
0
7
0
% E
% Phe:
0
60
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
60
0
0
0
0
0
7
7
7
% G
% His:
47
0
0
7
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
47
0
0
0
0
0
0
20
7
0
54
0
7
% I
% Lys:
0
0
0
0
7
0
0
7
7
14
0
7
7
0
0
% K
% Leu:
0
0
14
7
7
14
0
7
0
47
20
0
20
7
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
7
0
7
0
47
7
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
7
0
14
7
0
0
7
0
60
0
0
54
0
% P
% Gln:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
0
7
0
7
0
7
0
54
0
0
0
0
14
47
% R
% Ser:
7
7
0
0
7
14
14
47
14
7
7
14
0
0
14
% S
% Thr:
0
0
0
7
7
0
0
20
0
0
0
0
7
0
7
% T
% Val:
0
0
7
0
0
0
0
7
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _