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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UAP1
All Species:
15.76
Human Site:
S496
Identified Species:
24.76
UniProt:
Q16222
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16222
NP_003106.3
522
58769
S496
Y
A
G
E
G
L
E
S
Y
V
A
D
K
E
F
Chimpanzee
Pan troglodytes
XP_001174283
522
58736
S496
Y
A
G
E
G
L
E
S
Y
V
A
D
K
E
F
Rhesus Macaque
Macaca mulatta
XP_001118199
522
58639
S496
Y
A
G
E
G
L
E
S
Y
V
A
D
K
E
F
Dog
Lupus familis
XP_849867
522
58787
S496
Y
A
G
E
G
I
E
S
Y
V
A
D
K
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91YN5
522
58590
G496
Y
A
G
E
G
L
E
G
Y
V
A
D
K
E
F
Rat
Rattus norvegicus
XP_573497
521
58376
G495
Y
A
G
E
G
L
E
G
Y
V
A
D
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509643
385
43006
V377
G
I
K
M
E
K
F
V
F
D
I
F
Q
F
A
Chicken
Gallus gallus
XP_415568
501
55961
E492
C
S
P
F
I
L
D
E
D
K
A
E
M
L
R
Frog
Xenopus laevis
NP_001091348
523
58611
P495
Y
A
G
E
G
L
E
P
Y
V
H
N
Q
E
F
Zebra Danio
Brachydanio rerio
Q7ZWD4
505
56395
E495
K
S
P
F
I
L
D
E
N
E
A
K
N
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609032
520
58196
D511
T
S
P
V
Y
L
R
D
S
R
D
P
L
H
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18493
484
53478
S474
I
S
D
S
A
L
E
S
D
H
S
I
N
K
F
Sea Urchin
Strong. purpuratus
XP_779933
489
55054
N477
P
I
L
L
N
Q
A
N
I
I
A
E
K
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64765
502
55741
A487
Y
A
G
E
N
L
E
A
I
C
R
G
R
T
F
Baker's Yeast
Sacchar. cerevisiae
P43123
477
53458
D469
Q
F
K
G
K
V
F
D
R
S
G
I
V
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
96.1
N.A.
93.4
93.3
N.A.
48.4
58.8
73.6
56.7
N.A.
50.3
N.A.
36.4
57.8
Protein Similarity:
100
100
99.2
98.8
N.A.
96.9
96.5
N.A.
61.2
72
85.4
71.8
N.A.
69.7
N.A.
55.3
73.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
13.3
73.3
13.3
N.A.
6.6
N.A.
26.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
33.3
86.6
26.6
N.A.
13.3
N.A.
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
38.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
55.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
0
7
0
7
7
0
0
60
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
14
14
14
7
7
40
0
7
0
% D
% Glu:
0
0
0
54
7
0
60
14
0
7
0
14
0
40
14
% E
% Phe:
0
7
0
14
0
0
14
0
7
0
0
7
0
7
60
% F
% Gly:
7
0
54
7
47
0
0
14
0
0
7
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% H
% Ile:
7
14
0
0
14
7
0
0
14
7
7
14
0
0
0
% I
% Lys:
7
0
14
0
7
7
0
0
0
7
0
7
47
7
0
% K
% Leu:
0
0
7
7
0
74
0
0
0
0
0
0
7
20
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
14
0
0
7
7
0
0
7
14
0
0
% N
% Pro:
7
0
20
0
0
0
0
7
0
0
0
7
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
0
0
0
0
0
14
7
0
% Q
% Arg:
0
0
0
0
0
0
7
0
7
7
7
0
7
0
7
% R
% Ser:
0
27
0
7
0
0
0
34
7
7
7
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
0
7
0
7
0
7
0
47
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
7
0
0
0
47
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _