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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F4
All Species:
10.3
Human Site:
S325
Identified Species:
20.61
UniProt:
Q16254
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16254
NP_001941.2
413
43960
S325
S
S
N
S
N
S
S
S
S
S
G
P
N
P
S
Chimpanzee
Pan troglodytes
XP_511025
426
45548
P344
S
S
S
S
G
P
N
P
S
T
S
F
E
P
I
Rhesus Macaque
Macaca mulatta
XP_001088067
416
44276
S328
S
S
S
S
N
S
S
S
L
S
G
P
N
P
S
Dog
Lupus familis
XP_853975
409
43531
N326
N
S
S
S
S
G
P
N
P
S
T
S
F
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0K9
410
43815
P326
S
S
S
S
S
S
G
P
N
P
S
T
S
F
E
Rat
Rattus norvegicus
Q62814
300
33206
K219
S
T
S
V
T
P
P
K
S
T
M
A
A
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506812
384
40812
P299
L
G
I
G
E
T
V
P
M
G
G
P
L
F
G
Chicken
Gallus gallus
XP_001231948
414
44371
S326
S
S
A
S
L
D
S
S
S
V
L
P
S
P
S
Frog
Xenopus laevis
NP_001086706
375
40890
S294
S
N
D
S
P
D
P
S
T
S
F
Q
P
I
K
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
D305
L
Q
S
S
A
S
L
D
S
S
S
L
P
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624285
300
34327
S218
F
R
P
P
K
G
I
S
K
P
D
P
V
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
E275
V
A
E
P
M
L
T
E
T
K
I
K
E
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
97.5
93.4
N.A.
92.4
52.2
N.A.
37
71.2
67.8
63.4
N.A.
N.A.
38
N.A.
50.6
Protein Similarity:
100
94.5
98.5
94.4
N.A.
95.1
62.4
N.A.
47.7
78.7
77.9
74.8
N.A.
N.A.
53.7
N.A.
63.4
P-Site Identity:
100
33.3
86.6
20
N.A.
26.6
13.3
N.A.
13.3
60
26.6
33.3
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
53.3
93.3
46.6
N.A.
53.3
40
N.A.
20
66.6
46.6
40
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
0
0
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
17
0
9
0
0
9
0
0
9
0
% D
% Glu:
0
0
9
0
9
0
0
9
0
0
0
0
17
17
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
9
9
9
17
0
% F
% Gly:
0
9
0
9
9
17
9
0
0
9
25
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
9
0
0
17
9
% I
% Lys:
0
0
0
0
9
0
0
9
9
9
0
9
0
0
9
% K
% Leu:
17
0
0
0
9
9
9
0
9
0
9
9
9
0
0
% L
% Met:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
9
9
9
0
17
0
9
9
9
0
0
0
17
0
9
% N
% Pro:
0
0
9
17
9
17
25
25
9
17
0
42
17
34
9
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
59
50
50
67
17
34
25
42
42
42
25
9
17
0
42
% S
% Thr:
0
9
0
0
9
9
9
0
17
17
9
9
0
0
0
% T
% Val:
9
0
0
9
0
0
9
0
0
9
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _