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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGFBP7
All Species:
9.09
Human Site:
Y80
Identified Species:
33.33
UniProt:
Q16270
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16270
NP_001544.1
282
29130
Y80
G
G
G
A
G
R
G
Y
C
A
P
G
M
E
C
Chimpanzee
Pan troglodytes
XP_517274
340
35857
Y138
G
G
G
A
G
R
G
Y
C
A
P
G
M
E
C
Rhesus Macaque
Macaca mulatta
XP_001083041
282
29063
Y80
G
G
G
A
G
R
G
Y
C
A
P
G
M
E
C
Dog
Lupus familis
XP_850270
282
28881
H80
G
G
G
A
G
R
G
H
C
A
P
G
M
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61581
281
28951
H79
G
G
A
A
G
R
G
H
C
A
P
G
M
E
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519033
87
9478
Chicken
Gallus gallus
Frog
Xenopus laevis
P51609
343
38052
G92
G
T
C
M
A
L
E
G
N
S
C
V
F
D
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
98.9
93.9
N.A.
91.1
N.A.
N.A.
26.6
N.A.
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77
99.6
96.4
N.A.
94.3
N.A.
N.A.
29.4
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
72
15
0
0
0
0
72
0
0
0
0
0
% A
% Cys:
0
0
15
0
0
0
0
0
72
0
15
0
0
0
72
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
0
0
0
15
0
0
0
0
0
0
72
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
86
72
58
0
72
0
72
15
0
0
0
72
0
0
15
% G
% His:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
72
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _