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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A2
All Species:
26.06
Human Site:
S461
Identified Species:
52.12
UniProt:
Q16348
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16348
NP_066568.3
729
81783
S461
K
L
H
L
K
T
K
S
Q
D
F
H
F
H
L
Chimpanzee
Pan troglodytes
XP_001165943
729
81745
S461
K
L
H
L
K
T
K
S
Q
D
F
H
F
H
L
Rhesus Macaque
Macaca mulatta
NP_001028125
729
81543
S461
K
L
H
L
K
T
K
S
Q
N
F
H
F
H
L
Dog
Lupus familis
XP_545128
740
82954
S472
Q
L
H
L
K
T
R
S
Q
D
F
H
F
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES07
729
81614
S461
K
L
R
L
E
T
K
S
Q
D
L
H
F
H
L
Rat
Rattus norvegicus
Q63424
729
81301
S461
K
L
H
L
E
A
K
S
Q
D
L
H
F
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
T423
A
L
N
L
R
D
K
T
E
F
M
K
L
D
V
Chicken
Gallus gallus
XP_422093
776
86229
Q508
H
L
I
L
N
G
E
Q
Q
S
L
R
F
I
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034917
719
79569
S444
S
L
P
L
T
G
E
S
Q
L
Q
N
V
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
E446
L
Q
M
T
E
S
K
E
Y
T
F
N
A
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
G429
G
I
Y
T
F
N
T
G
L
K
N
E
S
Q
E
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
G431
T
G
P
I
D
V
A
G
G
T
K
K
I
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
87
N.A.
82.8
82.8
N.A.
48.5
55.7
N.A.
54.7
N.A.
38.3
N.A.
34.2
41.5
Protein Similarity:
100
99.8
98.3
92.9
N.A.
90.8
90.5
N.A.
63.6
70.7
N.A.
71.8
N.A.
58.2
N.A.
54.5
59.6
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
20
33.3
N.A.
26.6
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
53.3
40
N.A.
46.6
N.A.
33.3
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
0
0
0
42
0
0
0
17
0
% D
% Glu:
0
0
0
0
25
0
17
9
9
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
9
42
0
59
0
9
% F
% Gly:
9
9
0
0
0
17
0
17
9
0
0
0
0
0
0
% G
% His:
9
0
42
0
0
0
0
0
0
0
0
50
0
42
0
% H
% Ile:
0
9
9
9
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
42
0
0
0
34
0
59
0
0
9
9
17
0
0
0
% K
% Leu:
9
75
0
75
0
0
0
0
9
9
25
0
9
0
59
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
0
0
9
9
17
0
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
9
9
0
0
0
0
0
9
67
0
9
0
0
17
0
% Q
% Arg:
0
0
9
0
9
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
9
0
0
0
0
9
0
59
0
9
0
0
9
0
0
% S
% Thr:
9
0
0
17
9
42
9
9
0
17
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _