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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A2
All Species:
21.21
Human Site:
S497
Identified Species:
42.42
UniProt:
Q16348
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16348
NP_066568.3
729
81783
S497
V
I
R
E
D
G
N
S
I
S
S
M
M
V
K
Chimpanzee
Pan troglodytes
XP_001165943
729
81745
S497
V
I
R
E
D
G
N
S
I
S
S
M
M
V
K
Rhesus Macaque
Macaca mulatta
NP_001028125
729
81543
S497
V
I
R
E
D
G
N
S
I
S
S
M
M
V
K
Dog
Lupus familis
XP_545128
740
82954
N508
I
I
R
E
D
G
K
N
I
Y
S
M
M
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES07
729
81614
S497
V
V
H
E
N
G
E
S
L
S
S
M
L
V
K
Rat
Rattus norvegicus
Q63424
729
81301
S497
L
I
H
Q
D
G
E
S
I
S
S
M
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
L459
K
E
G
Q
R
Q
T
L
L
L
W
S
P
S
E
Chicken
Gallus gallus
XP_422093
776
86229
S544
I
V
F
E
A
E
G
S
L
S
S
R
L
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034917
719
79569
S480
L
L
H
P
P
A
Q
S
G
G
S
V
C
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
L482
Y
F
L
A
Q
D
K
L
V
E
F
A
D
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
K465
E
V
V
K
F
D
Y
K
V
E
K
T
D
N
G
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
Q467
F
S
A
S
L
G
S
Q
L
V
E
S
V
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
87
N.A.
82.8
82.8
N.A.
48.5
55.7
N.A.
54.7
N.A.
38.3
N.A.
34.2
41.5
Protein Similarity:
100
99.8
98.3
92.9
N.A.
90.8
90.5
N.A.
63.6
70.7
N.A.
71.8
N.A.
58.2
N.A.
54.5
59.6
P-Site Identity:
100
100
100
73.3
N.A.
60
66.6
N.A.
0
26.6
N.A.
13.3
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
20
60
N.A.
33.3
N.A.
6.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
42
17
0
0
0
0
0
0
17
0
0
% D
% Glu:
9
9
0
50
0
9
17
0
0
17
9
0
0
0
9
% E
% Phe:
9
9
9
0
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
59
9
0
9
9
0
0
0
9
9
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
42
0
0
0
0
0
0
42
0
0
0
0
17
0
% I
% Lys:
9
0
0
9
0
0
17
9
0
0
9
0
0
0
50
% K
% Leu:
17
9
9
0
9
0
0
17
34
9
0
0
25
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
50
34
0
0
% M
% Asn:
0
0
0
0
9
0
25
9
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
17
9
9
9
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
0
9
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
9
0
0
9
59
0
50
67
17
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% T
% Val:
34
25
9
0
0
0
0
0
17
9
0
9
9
50
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _