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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A2
All Species:
17.58
Human Site:
T449
Identified Species:
35.15
UniProt:
Q16348
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16348
NP_066568.3
729
81783
T449
S
I
K
S
F
Q
K
T
P
H
Y
S
K
L
H
Chimpanzee
Pan troglodytes
XP_001165943
729
81745
T449
S
I
K
S
F
Q
K
T
P
H
Y
S
K
L
H
Rhesus Macaque
Macaca mulatta
NP_001028125
729
81543
T449
S
I
K
S
F
Q
K
T
P
Q
Y
S
K
L
H
Dog
Lupus familis
XP_545128
740
82954
M460
S
I
R
S
F
Q
K
M
P
H
Y
A
Q
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES07
729
81614
T449
S
I
S
S
F
Q
N
T
T
H
Y
S
K
L
R
Rat
Rattus norvegicus
Q63424
729
81301
T449
S
V
S
S
F
Q
N
T
T
H
Y
S
K
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
G411
S
M
N
V
I
F
P
G
K
E
A
V
A
L
N
Chicken
Gallus gallus
XP_422093
776
86229
P496
P
V
E
A
F
Q
N
P
D
E
Y
S
H
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034917
719
79569
P432
P
L
K
P
Y
E
E
P
S
G
Y
S
S
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
W434
V
I
E
P
L
N
V
W
E
D
L
S
L
Q
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
T417
G
M
L
P
K
G
R
T
E
L
D
A
G
I
Y
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
E419
S
P
C
P
I
N
V
E
S
K
F
Y
T
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
87
N.A.
82.8
82.8
N.A.
48.5
55.7
N.A.
54.7
N.A.
38.3
N.A.
34.2
41.5
Protein Similarity:
100
99.8
98.3
92.9
N.A.
90.8
90.5
N.A.
63.6
70.7
N.A.
71.8
N.A.
58.2
N.A.
54.5
59.6
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
73.3
N.A.
13.3
33.3
N.A.
26.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
26.6
53.3
N.A.
53.3
N.A.
20
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
9
17
9
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% D
% Glu:
0
0
17
0
0
9
9
9
17
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
59
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
9
0
9
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
42
0
0
9
0
42
% H
% Ile:
0
50
0
0
17
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
34
0
9
0
34
0
9
9
0
0
42
0
0
% K
% Leu:
0
9
9
0
9
0
0
0
0
9
9
0
9
75
0
% L
% Met:
0
17
0
0
0
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
17
25
0
0
0
0
0
0
0
9
% N
% Pro:
17
9
0
34
0
0
9
17
34
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
59
0
0
0
9
0
0
9
9
0
% Q
% Arg:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
9
% R
% Ser:
67
0
17
50
0
0
0
0
17
0
0
67
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
17
0
0
0
9
0
0
% T
% Val:
9
17
0
9
0
0
17
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
67
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _