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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A2
All Species:
23.94
Human Site:
Y543
Identified Species:
47.88
UniProt:
Q16348
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16348
NP_066568.3
729
81783
Y543
S
L
N
V
G
E
D
Y
G
V
S
A
Y
R
T
Chimpanzee
Pan troglodytes
XP_001165943
729
81745
Y543
S
L
N
V
G
E
D
Y
G
V
S
A
Y
R
T
Rhesus Macaque
Macaca mulatta
NP_001028125
729
81543
Y543
S
L
N
V
G
E
D
Y
G
V
S
A
Y
R
T
Dog
Lupus familis
XP_545128
740
82954
Y554
S
L
S
V
G
E
D
Y
G
V
S
A
Y
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES07
729
81614
Y543
P
L
S
V
G
K
D
Y
G
V
S
E
Y
R
T
Rat
Rattus norvegicus
Q63424
729
81301
Y543
P
L
S
V
G
K
D
Y
G
V
S
A
Y
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506250
701
78013
Q505
T
V
A
G
S
N
F
Q
D
V
L
P
R
N
A
Chicken
Gallus gallus
XP_422093
776
86229
Y590
F
I
P
V
Q
R
N
Y
G
V
S
G
Y
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034917
719
79569
N526
E
E
V
H
A
S
A
N
Y
G
I
S
R
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91679
743
82227
L528
A
T
S
Q
E
P
P
L
T
L
D
K
G
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01840
701
77949
D511
L
K
S
G
S
Y
V
D
V
I
P
G
I
I
S
Sea Urchin
Strong. purpuratus
XP_792746
715
78418
L513
L
N
N
V
S
S
S
L
D
V
E
P
G
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
87
N.A.
82.8
82.8
N.A.
48.5
55.7
N.A.
54.7
N.A.
38.3
N.A.
34.2
41.5
Protein Similarity:
100
99.8
98.3
92.9
N.A.
90.8
90.5
N.A.
63.6
70.7
N.A.
71.8
N.A.
58.2
N.A.
54.5
59.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
6.6
40
N.A.
0
N.A.
0
N.A.
0
20
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
20
53.3
N.A.
6.6
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
9
0
0
0
0
42
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
9
17
0
9
0
0
0
0
% D
% Glu:
9
9
0
0
9
34
0
0
0
0
9
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
50
0
0
0
59
9
0
17
17
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
9
9
0
9
9
9
% I
% Lys:
0
9
0
0
0
17
0
0
0
0
0
9
0
0
0
% K
% Leu:
17
50
0
0
0
0
0
17
0
9
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
34
0
0
9
9
9
0
0
0
0
0
25
0
% N
% Pro:
17
0
9
0
0
9
9
0
0
0
9
17
0
0
0
% P
% Gln:
0
0
0
9
9
0
0
9
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
17
42
0
% R
% Ser:
34
0
42
0
25
17
9
0
0
0
59
9
0
9
9
% S
% Thr:
9
9
0
0
0
0
0
0
9
0
0
0
0
9
50
% T
% Val:
0
9
9
67
0
0
9
0
9
75
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
59
9
0
0
0
59
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _