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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXT1
All Species:
19.09
Human Site:
T255
Identified Species:
35
UniProt:
Q16394
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16394
NP_000118.2
746
86255
T255
R
G
F
L
K
F
N
T
I
P
P
L
R
K
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108202
675
74245
G209
E
A
H
P
L
R
G
G
A
P
G
Q
L
Q
Q
Dog
Lupus familis
XP_539145
746
86191
T255
R
G
F
L
K
F
N
T
I
P
P
L
R
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P97464
746
86289
T255
R
G
F
L
K
F
N
T
I
P
P
L
R
K
Y
Rat
Rattus norvegicus
NP_001101455
670
74649
G204
P
E
A
H
P
L
K
G
G
A
P
G
S
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509292
443
50957
Chicken
Gallus gallus
XP_418396
865
98072
T374
K
G
F
L
R
F
N
T
I
P
P
L
R
K
Y
Frog
Xenopus laevis
NP_001083782
738
84810
N247
K
G
F
L
R
F
N
N
I
P
P
M
R
K
Y
Zebra Danio
Brachydanio rerio
Q5IGR7
741
85103
T250
R
G
Y
L
K
Y
N
T
I
P
P
F
R
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V730
760
87290
N252
T
G
T
V
Q
S
N
N
F
P
A
N
K
K
Y
Honey Bee
Apis mellifera
XP_391845
711
82974
G242
K
Y
I
A
A
F
K
G
K
R
Y
V
H
G
I
Nematode Worm
Caenorhab. elegans
O01704
378
44434
Sea Urchin
Strong. purpuratus
XP_783281
693
79753
T227
L
F
G
I
G
S
D
T
R
N
A
L
Y
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
43.9
99.1
N.A.
99.3
42.3
N.A.
58
78.2
88.4
83.6
N.A.
54.4
55.6
26.2
52.1
Protein Similarity:
100
N.A.
60.4
99.5
N.A.
99.7
58.7
N.A.
58.9
81
94.2
91.9
N.A.
69.8
70.2
37.4
68.2
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
6.6
N.A.
0
86.6
73.3
80
N.A.
33.3
6.6
0
13.3
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
6.6
N.A.
0
100
93.3
93.3
N.A.
53.3
20
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
0
8
8
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
39
0
0
47
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
54
8
0
8
0
8
24
8
0
8
8
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
8
8
0
0
0
0
47
0
0
0
0
0
8
% I
% Lys:
24
0
0
0
31
0
16
0
8
0
0
0
8
54
0
% K
% Leu:
8
0
0
47
8
8
0
0
0
0
0
39
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
54
16
0
8
0
8
0
0
0
% N
% Pro:
8
0
0
8
8
0
0
0
0
62
54
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
16
% Q
% Arg:
31
0
0
0
16
8
0
0
8
8
0
0
47
0
0
% R
% Ser:
0
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
47
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
8
0
0
0
0
8
0
8
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _