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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXT1 All Species: 26.06
Human Site: Y131 Identified Species: 47.78
UniProt: Q16394 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16394 NP_000118.2 746 86255 Y131 G E K I A E S Y Q N I L A A I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108202 675 74245 T87 N W G A C F D T S K C R G D G
Dog Lupus familis XP_539145 746 86191 Y131 G E K I A E S Y Q N I L A A I
Cat Felis silvestris
Mouse Mus musculus P97464 746 86289 Y131 G E K I A E S Y Q N I L A A I
Rat Rattus norvegicus NP_001101455 670 74649 A82 G S S C T W G A C F D T S K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509292 443 50957
Chicken Gallus gallus XP_418396 865 98072 Y250 G E K I A E S Y Q N V L A A I
Frog Xenopus laevis NP_001083782 738 84810 Y123 G D K L S D S Y Q H I L A A I
Zebra Danio Brachydanio rerio Q5IGR7 741 85103 Y126 G E K I S E S Y Q N I L S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V730 760 87290 Y127 A P P T S A N Y Q K I L T A I
Honey Bee Apis mellifera XP_391845 711 82974 D120 E S R Y Y T S D P T R A C I F
Nematode Worm Caenorhab. elegans O01704 378 44434
Sea Urchin Strong. purpuratus XP_783281 693 79753 S105 E A C L F V T S I D T L D R D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 43.9 99.1 N.A. 99.3 42.3 N.A. 58 78.2 88.4 83.6 N.A. 54.4 55.6 26.2 52.1
Protein Similarity: 100 N.A. 60.4 99.5 N.A. 99.7 58.7 N.A. 58.9 81 94.2 91.9 N.A. 69.8 70.2 37.4 68.2
P-Site Identity: 100 N.A. 0 100 N.A. 100 6.6 N.A. 0 93.3 66.6 80 N.A. 40 6.6 0 6.6
P-Site Similarity: 100 N.A. 0 100 N.A. 100 13.3 N.A. 0 100 100 93.3 N.A. 53.3 13.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 31 8 0 8 0 0 0 8 39 47 0 % A
% Cys: 0 0 8 8 8 0 0 0 8 0 8 0 8 0 8 % C
% Asp: 0 8 0 0 0 8 8 8 0 8 8 0 8 8 8 % D
% Glu: 16 39 0 0 0 39 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 8 0 0 0 0 8 % F
% Gly: 54 0 8 0 0 0 8 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 39 0 0 0 0 8 0 47 0 0 8 54 % I
% Lys: 0 0 47 0 0 0 0 0 0 16 0 0 0 8 0 % K
% Leu: 0 0 0 16 0 0 0 0 0 0 0 62 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 0 39 0 0 0 0 0 % N
% Pro: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 8 8 0 8 0 % R
% Ser: 0 16 8 0 24 0 54 8 8 0 0 0 16 0 0 % S
% Thr: 0 0 0 8 8 8 8 8 0 8 8 8 8 8 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _