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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD5
All Species:
22.12
Human Site:
S445
Identified Species:
60.83
UniProt:
Q16401
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16401
NP_005038.1
504
56196
S445
V
E
Y
V
V
D
R
S
V
E
H
D
K
A
S
Chimpanzee
Pan troglodytes
XP_520224
504
56150
S445
V
E
Y
V
V
D
R
S
V
E
H
D
K
A
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531929
523
57924
S464
V
E
Y
V
M
D
R
S
V
E
H
D
K
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJY1
504
55954
S445
V
E
F
V
M
D
R
S
V
E
H
D
K
A
S
Rat
Rattus norvegicus
NP_001100039
330
36681
V272
E
F
V
M
D
R
S
V
E
H
D
K
T
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012815
504
55709
S445
V
E
Y
I
V
D
R
S
V
E
P
D
K
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017573
505
55198
S446
V
E
W
V
M
D
R
S
V
G
S
G
K
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120302
443
49482
R385
L
V
E
F
L
L
D
R
N
I
E
S
F
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793127
358
39447
T300
E
Y
L
L
D
R
S
T
E
P
D
K
E
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
87
N.A.
89.8
59.7
N.A.
N.A.
74.8
N.A.
57.6
N.A.
N.A.
31.9
N.A.
30.3
Protein Similarity:
100
100
N.A.
91.7
N.A.
96.8
62.9
N.A.
N.A.
87
N.A.
77.6
N.A.
N.A.
51.5
N.A.
45
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
0
N.A.
N.A.
86.6
N.A.
53.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
N.A.
93.3
N.A.
73.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
56
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
23
67
12
0
0
0
23
56
0
0
0
% D
% Glu:
23
67
12
0
0
0
0
0
23
56
12
0
12
12
12
% E
% Phe:
0
12
12
12
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
45
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
23
67
12
23
% K
% Leu:
12
0
12
12
12
12
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
34
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
23
67
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
23
67
0
0
12
12
0
12
56
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% T
% Val:
67
12
12
56
34
0
0
12
67
0
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
45
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _