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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMD5
All Species:
13.33
Human Site:
S486
Identified Species:
36.67
UniProt:
Q16401
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16401
NP_005038.1
504
56196
S486
L
R
L
R
T
Y
L
S
E
G
P
Y
Y
V
K
Chimpanzee
Pan troglodytes
XP_520224
504
56150
S486
L
R
L
R
T
Y
L
S
E
G
P
Y
Y
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531929
523
57924
S505
L
R
L
R
T
Y
L
S
E
G
P
Y
Y
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJY1
504
55954
S486
L
R
L
R
A
Y
L
S
E
G
P
Y
Y
V
K
Rat
Rattus norvegicus
NP_001100039
330
36681
E313
R
L
R
T
Y
L
S
E
G
P
Y
Y
V
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012815
504
55709
N486
L
R
L
R
A
Y
L
N
E
G
P
Y
Y
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017573
505
55198
N487
L
K
L
K
T
Y
L
N
E
G
P
Y
Y
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120302
443
49482
Q426
R
F
R
E
F
V
N
Q
G
P
H
Y
V
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793127
358
39447
D341
R
L
K
E
Y
V
R
D
G
P
F
Y
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
87
N.A.
89.8
59.7
N.A.
N.A.
74.8
N.A.
57.6
N.A.
N.A.
31.9
N.A.
30.3
Protein Similarity:
100
100
N.A.
91.7
N.A.
96.8
62.9
N.A.
N.A.
87
N.A.
77.6
N.A.
N.A.
51.5
N.A.
45
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
N.A.
86.6
N.A.
73.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
N.A.
93.3
N.A.
93.3
N.A.
N.A.
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
23
0
0
0
12
67
0
0
0
0
0
0
% E
% Phe:
0
12
0
0
12
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
34
67
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
12
12
12
0
0
0
0
0
0
0
0
0
12
56
% K
% Leu:
67
23
67
0
0
12
67
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
34
67
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
34
56
23
56
0
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
12
45
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
45
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
23
0
0
0
0
0
0
34
67
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
67
0
0
0
0
12
100
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _