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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIK5
All Species:
20.3
Human Site:
S146
Identified Species:
44.67
UniProt:
Q16478
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16478
NP_002079.3
980
109265
S146
Y
P
S
N
E
D
V
S
L
A
V
S
R
I
L
Chimpanzee
Pan troglodytes
Q5IS46
956
107246
S147
H
P
S
N
T
D
I
S
V
A
V
A
G
I
L
Rhesus Macaque
Macaca mulatta
XP_001106948
956
107232
S147
H
P
S
N
T
D
I
S
V
A
V
A
G
I
L
Dog
Lupus familis
XP_853030
862
96920
N111
A
S
S
S
I
I
S
N
I
C
G
E
K
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61626
979
109243
S146
Y
P
S
N
E
D
V
S
L
A
V
S
R
I
L
Rat
Rattus norvegicus
Q63273
979
109257
S146
Y
P
S
N
E
D
V
S
L
A
V
S
R
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509334
767
86258
V21
A
P
A
P
R
S
A
V
T
T
P
R
P
A
S
Chicken
Gallus gallus
P19439
487
54337
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q68Y21
1009
113606
T143
R
A
Q
P
D
D
Y
T
L
F
V
R
P
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03445
991
111650
L181
L
Y
D
S
H
D
G
L
L
R
L
Q
Q
I
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34299
962
108124
S150
V
S
V
R
P
P
I
S
E
L
L
A
D
F
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
67.9
63.3
N.A.
98.7
98.8
N.A.
72.3
21.4
N.A.
25.3
N.A.
33
N.A.
30.5
N.A.
Protein Similarity:
100
78.9
78.9
73.8
N.A.
99.1
99.1
N.A.
73.9
32.3
N.A.
45.1
N.A.
53
N.A.
48.2
N.A.
P-Site Identity:
100
60
60
6.6
N.A.
100
100
N.A.
6.6
0
N.A.
20
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
86.6
86.6
40
N.A.
100
100
N.A.
13.3
0
N.A.
40
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
0
0
0
10
0
0
46
0
28
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
64
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
28
0
0
0
10
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
10
0
19
0
0
% G
% His:
19
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
28
0
10
0
0
0
0
55
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
0
0
0
0
10
46
10
19
0
0
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
46
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
55
0
19
10
10
0
0
0
0
10
0
19
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
10
0
0
10
10
0
0
0
0
10
0
19
28
0
0
% R
% Ser:
0
19
55
19
0
10
10
55
0
0
0
28
0
0
10
% S
% Thr:
0
0
0
0
19
0
0
10
10
10
0
0
0
0
0
% T
% Val:
10
0
10
0
0
0
28
10
19
0
55
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
28
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _