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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN2 All Species: 16.67
Human Site: S132 Identified Species: 28.21
UniProt: Q16513 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16513 NP_006247.1 984 112035 S132 P N N D P R C S T S N N R L K
Chimpanzee Pan troglodytes XP_001145367 984 112028 S132 P N N D P R C S T S N N R L K
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 W211 V A S G P R P W A E Q L R A R
Dog Lupus familis XP_547295 1021 115999 S170 P N S D P R C S T S S N R L M
Cat Felis silvestris
Mouse Mus musculus Q8BWW9 983 111611 S132 P N S D S R S S T S N N R L M
Rat Rattus norvegicus O08874 985 112050 S132 P N S D S R S S T S N N R R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 E199 S P D P C R W E E K P V A R R
Chicken Gallus gallus XP_422357 1013 114806 P160 P N S D P R F P T N N R L M A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700704 970 110327 C120 P K S E S R T C T S S S R L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133
Sea Urchin Strong. purpuratus XP_787090 799 90414 T30 Q Q S R Q I P T G E K E A G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 Q198 P N D I M D N Q Q P K F R R K
Red Bread Mold Neurospora crassa P87253 1142 127954 Q160 P H L G P R I Q L M L S Q I Q
Conservation
Percent
Protein Identity: 100 99.6 46.1 92.8 N.A. 94.6 92.6 N.A. 53.9 87 N.A. 76.4 N.A. 28.3 N.A. 27.6 48.4
Protein Similarity: 100 99.9 63.2 94.7 N.A. 97.2 95.3 N.A. 68.2 91.9 N.A. 85 N.A. 42.3 N.A. 43.7 61.3
P-Site Identity: 100 100 20 80 N.A. 73.3 66.6 N.A. 6.6 46.6 N.A. 40 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 33.3 93.3 N.A. 80 73.3 N.A. 20 66.6 N.A. 66.6 N.A. 0 N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 45.6 45.9
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 8 0 0 0 15 8 15 % A
% Cys: 0 0 0 0 8 0 22 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 43 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 8 8 15 0 8 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 15 0 0 0 0 8 0 0 0 0 8 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 8 0 0 0 0 0 0 8 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 8 15 0 0 0 22 % K
% Leu: 0 0 8 0 0 0 0 0 8 0 8 8 8 36 8 % L
% Met: 0 0 0 0 8 0 0 0 0 8 0 0 0 8 15 % M
% Asn: 0 50 15 0 0 0 8 0 0 8 36 36 0 0 0 % N
% Pro: 65 8 0 8 43 0 15 8 0 8 8 0 0 0 0 % P
% Gln: 8 8 0 0 8 0 0 15 8 0 8 0 8 0 8 % Q
% Arg: 0 0 0 8 0 72 0 0 0 0 0 8 58 22 15 % R
% Ser: 8 0 50 0 22 0 15 36 0 43 15 15 0 0 0 % S
% Thr: 0 0 0 0 0 0 8 8 50 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _