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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
15.76
Human Site:
S21
Identified Species:
26.67
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
S21
E
L
Q
G
D
S
R
S
L
P
F
S
E
N
V
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
S21
E
L
Q
G
D
S
R
S
L
P
F
S
E
N
V
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
P37
E
S
R
G
I
L
D
P
R
E
A
L
E
R
G
Dog
Lupus familis
XP_547295
1021
115999
S59
Y
F
H
G
D
S
R
S
L
P
F
S
E
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T21
E
L
Q
G
D
S
R
T
L
P
F
S
E
N
V
Rat
Rattus norvegicus
O08874
985
112050
P21
E
L
Q
V
D
S
R
P
L
P
F
S
E
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
G76
V
W
S
P
A
L
L
G
S
P
W
W
G
R
F
Chicken
Gallus gallus
XP_422357
1013
114806
S49
Y
F
S
G
D
A
K
S
L
L
V
S
E
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
L21
Q
L
G
L
G
H
N
L
D
L
S
D
T
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
L27
I
I
R
G
A
S
A
L
K
K
K
T
S
N
V
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A24
E
K
A
L
I
N
A
A
Q
A
M
R
Q
Q
T
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
20
80
N.A.
93.3
86.6
N.A.
6.6
46.6
N.A.
13.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
26.6
80
N.A.
100
86.6
N.A.
13.3
66.6
N.A.
20
N.A.
0
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
15
8
15
8
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
43
0
8
0
8
0
0
8
0
0
0
% D
% Glu:
43
0
0
0
0
0
0
0
0
8
0
0
50
0
0
% E
% Phe:
0
15
0
0
0
0
0
0
0
0
36
0
0
0
8
% F
% Gly:
0
0
8
50
8
0
0
8
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
8
8
8
0
0
0
0
% K
% Leu:
0
36
0
15
0
15
8
15
43
15
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
8
0
0
0
15
0
43
0
0
0
0
0
% P
% Gln:
8
0
29
0
0
0
0
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
15
0
0
0
36
0
8
0
0
8
0
15
0
% R
% Ser:
0
8
15
0
0
43
0
29
8
0
8
43
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
8
% T
% Val:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
50
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _