Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN2 All Species: 21.52
Human Site: S360 Identified Species: 36.41
UniProt: Q16513 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16513 NP_006247.1 984 112035 S360 S V A L P G W S P S E T R S S
Chimpanzee Pan troglodytes XP_001145367 984 112028 S360 S V A L P G W S P S E T R S S
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 G410 Q L L A A V P G R S P A A A L
Dog Lupus familis XP_547295 1021 115999 S397 S V A L P G W S P S E T R S S
Cat Felis silvestris
Mouse Mus musculus Q8BWW9 983 111611 S359 S V A L P G W S P S D N R S S
Rat Rattus norvegicus O08874 985 112050 S361 S V A L P G W S P S E N R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 G397 E L L R A V P G R S R V A T V
Chicken Gallus gallus XP_422357 1013 114806 S386 S V T L P G W S P N E V R T T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700704 970 110327 W355 T S V P L P G W S P S E T R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 R59 R A G F N R R R G A M R R R V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 N132 V V E M H G T N V E D V H S H
Sea Urchin Strong. purpuratus XP_787090 799 90414 K224 N E I S A I M K L D S V L V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 L485 H R I P H R F L P T S N R G T
Red Bread Mold Neurospora crassa P87253 1142 127954 P400 M I P P Q A P P P S Q V V S Q
Conservation
Percent
Protein Identity: 100 99.6 46.1 92.8 N.A. 94.6 92.6 N.A. 53.9 87 N.A. 76.4 N.A. 28.3 N.A. 27.6 48.4
Protein Similarity: 100 99.9 63.2 94.7 N.A. 97.2 95.3 N.A. 68.2 91.9 N.A. 85 N.A. 42.3 N.A. 43.7 61.3
P-Site Identity: 100 100 6.6 100 N.A. 86.6 93.3 N.A. 6.6 66.6 N.A. 6.6 N.A. 6.6 N.A. 20 0
P-Site Similarity: 100 100 20 100 N.A. 93.3 93.3 N.A. 20 86.6 N.A. 13.3 N.A. 13.3 N.A. 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 45.6 45.9
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 36 8 22 8 0 0 0 8 0 8 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 15 0 0 0 0 % D
% Glu: 8 8 8 0 0 0 0 0 0 8 36 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 50 8 15 8 0 0 0 0 8 8 % G
% His: 8 0 0 0 15 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 0 8 15 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 0 15 15 43 8 0 0 8 8 0 0 0 8 0 8 % L
% Met: 8 0 0 8 0 0 8 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 8 0 8 0 22 0 0 0 % N
% Pro: 0 0 8 22 43 8 22 8 58 8 8 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 8 8 0 8 0 15 8 8 15 0 8 8 58 15 0 % R
% Ser: 43 8 0 8 0 0 0 43 8 58 22 0 0 50 43 % S
% Thr: 8 0 8 0 0 0 8 0 0 8 0 22 8 15 15 % T
% Val: 8 50 8 0 0 15 0 0 8 0 0 36 8 8 15 % V
% Trp: 0 0 0 0 0 0 43 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _