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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN2 All Species: 13.64
Human Site: S615 Identified Species: 23.08
UniProt: Q16513 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16513 NP_006247.1 984 112035 S615 D I Q N D R N S I L P K S Q S
Chimpanzee Pan troglodytes XP_001145367 984 112028 S615 D I E N D R N S I L P K S Q S
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S661 R G P S P P A S P T R K A P R
Dog Lupus familis XP_547295 1021 115999 S652 D I E N D R N S I L P K S P S
Cat Felis silvestris
Mouse Mus musculus Q8BWW9 983 111611 N614 N I E N D R N N L R P K S K S
Rat Rattus norvegicus O08874 985 112050 N616 D I E N D R N N M R P K S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 H643 G S N S R G S H R A G Q I P T
Chicken Gallus gallus XP_422357 1013 114806 V644 E N G R N S I V P K L Q P G I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700704 970 110327 P615 I V E H D T P P S A L Q L I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 K297 T G E T R P G K C S L L D F N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 G370 R S A S K V P G G T L S I H D
Sea Urchin Strong. purpuratus XP_787090 799 90414 D462 A Q E I S A M D D G T L M T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 T785 E T V S L A P T S T H P S R T
Red Bread Mold Neurospora crassa P87253 1142 127954 Y738 D Y A N I D A Y S S P Q A R P
Conservation
Percent
Protein Identity: 100 99.6 46.1 92.8 N.A. 94.6 92.6 N.A. 53.9 87 N.A. 76.4 N.A. 28.3 N.A. 27.6 48.4
Protein Similarity: 100 99.9 63.2 94.7 N.A. 97.2 95.3 N.A. 68.2 91.9 N.A. 85 N.A. 42.3 N.A. 43.7 61.3
P-Site Identity: 100 93.3 13.3 86.6 N.A. 60 66.6 N.A. 0 0 N.A. 6.6 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 26.6 93.3 N.A. 93.3 93.3 N.A. 26.6 20 N.A. 40 N.A. 13.3 N.A. 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 45.6 45.9
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 20
P-Site Similarity: N.A. N.A. N.A. N.A. 40 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 0 15 15 0 0 15 0 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 36 0 0 0 43 8 0 8 8 0 0 0 8 0 8 % D
% Glu: 15 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 15 8 0 0 8 8 8 8 8 8 0 0 8 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 8 0 0 8 0 % H
% Ile: 8 36 0 8 8 0 8 0 22 0 0 0 15 8 8 % I
% Lys: 0 0 0 0 8 0 0 8 0 8 0 43 0 15 0 % K
% Leu: 0 0 0 0 8 0 0 0 8 22 29 15 8 0 8 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 8 0 0 % M
% Asn: 8 8 8 43 8 0 36 15 0 0 0 0 0 0 15 % N
% Pro: 0 0 8 0 8 15 22 8 15 0 43 8 8 22 8 % P
% Gln: 0 8 8 0 0 0 0 0 0 0 0 29 0 15 0 % Q
% Arg: 15 0 0 8 15 36 0 0 8 15 8 0 0 15 8 % R
% Ser: 0 15 0 29 8 8 8 29 22 15 0 8 43 0 36 % S
% Thr: 8 8 0 8 0 8 0 8 0 22 8 0 0 8 15 % T
% Val: 0 8 8 0 0 8 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _