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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN2 All Species: 37.58
Human Site: S701 Identified Species: 63.59
UniProt: Q16513 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16513 NP_006247.1 984 112035 S701 V A R D E V D S L M C E K R I
Chimpanzee Pan troglodytes XP_001145367 984 112028 S701 V A R D E V D S L M C E K R I
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 L725 G N K V R P C L R K N K K K T
Dog Lupus familis XP_547295 1021 115999 S738 V A R D E V D S L M C E K R I
Cat Felis silvestris
Mouse Mus musculus Q8BWW9 983 111611 S700 V A R D E V D S L M C E K R I
Rat Rattus norvegicus O08874 985 112050 S702 V A R D E V D S L M C E K R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 S707 L S R D E L E S L H C E K R I
Chicken Gallus gallus XP_422357 1013 114806 S730 V A R D E V D S L M C E K R I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700704 970 110327 S687 V A R D E V E S L M C E K R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138 H361 I L A L A A N H P F L T A L H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 A434 K R I L S L A A K H P F L T A
Sea Urchin Strong. purpuratus XP_787090 799 90414 A526 C E K R I F E A A N S I R H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 S868 I Q N H D I E S A R A E K K V
Red Bread Mold Neurospora crassa P87253 1142 127954 S861 I E N D E V E S I R S E K R V
Conservation
Percent
Protein Identity: 100 99.6 46.1 92.8 N.A. 94.6 92.6 N.A. 53.9 87 N.A. 76.4 N.A. 28.3 N.A. 27.6 48.4
Protein Similarity: 100 99.9 63.2 94.7 N.A. 97.2 95.3 N.A. 68.2 91.9 N.A. 85 N.A. 42.3 N.A. 43.7 61.3
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 66.6 100 N.A. 93.3 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 93.3 100 N.A. 100 N.A. 13.3 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 27.2
Protein Similarity: N.A. N.A. N.A. N.A. 45.6 45.9
P-Site Identity: N.A. N.A. N.A. N.A. 20 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 60 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 8 0 8 8 8 15 15 0 8 0 8 0 8 % A
% Cys: 8 0 0 0 0 0 8 0 0 0 58 0 0 0 0 % C
% Asp: 0 0 0 65 8 0 43 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 0 0 65 0 36 0 0 0 0 72 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 8 0 8 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 8 0 15 0 0 0 8 8 % H
% Ile: 22 0 8 0 8 8 0 0 8 0 0 8 0 0 58 % I
% Lys: 8 0 15 0 0 0 0 0 8 8 0 8 79 15 0 % K
% Leu: 8 8 0 15 0 15 0 8 58 0 8 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % M
% Asn: 0 8 15 0 0 0 8 0 0 8 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 58 8 8 0 0 0 8 15 0 0 8 65 0 % R
% Ser: 0 8 0 0 8 0 0 72 0 0 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 8 % T
% Val: 50 0 0 8 0 58 0 0 0 0 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _