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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
17.27
Human Site:
T605
Identified Species:
29.23
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
T605
I
P
G
Q
D
S
E
T
V
F
D
I
Q
N
D
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
T605
T
P
G
Q
D
S
E
T
V
F
D
I
E
N
D
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
R651
K
R
P
H
M
E
P
R
T
R
R
G
P
S
P
Dog
Lupus familis
XP_547295
1021
115999
T642
T
P
A
Q
D
S
E
T
V
F
D
I
E
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
T604
I
P
G
Q
G
S
E
T
V
F
N
I
E
N
D
Rat
Rattus norvegicus
O08874
985
112050
T606
I
P
G
Q
G
S
E
T
V
F
D
I
E
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
M633
P
C
T
K
R
P
H
M
E
D
G
S
N
S
R
Chicken
Gallus gallus
XP_422357
1013
114806
F634
A
Q
D
D
V
S
T
F
D
F
E
N
G
R
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
L605
S
I
I
V
Q
S
G
L
E
E
I
V
E
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V287
A
V
T
G
S
G
G
V
G
A
T
G
E
T
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
T360
S
E
D
D
S
G
T
T
S
S
R
S
A
S
K
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
Q452
P
L
S
Q
T
Q
G
Q
H
G
A
Q
E
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
V775
Q
D
H
A
S
K
E
V
L
Q
E
T
V
S
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
N728
S
P
Q
Q
R
K
Y
N
P
A
D
Y
A
N
I
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
86.6
0
80
N.A.
80
86.6
N.A.
0
13.3
N.A.
13.3
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
93.3
6.6
86.6
N.A.
93.3
93.3
N.A.
13.3
26.6
N.A.
33.3
N.A.
6.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
0
0
0
0
0
15
8
0
15
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
15
15
22
0
0
0
8
8
36
0
0
0
43
% D
% Glu:
0
8
0
0
0
8
43
0
15
8
15
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
43
0
0
0
0
0
% F
% Gly:
0
0
29
8
15
15
22
0
8
8
8
15
8
0
0
% G
% His:
0
0
8
8
0
0
8
0
8
0
0
0
0
8
0
% H
% Ile:
22
8
8
0
0
0
0
0
0
0
8
36
0
8
8
% I
% Lys:
8
0
0
8
0
15
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
8
8
43
8
% N
% Pro:
15
43
8
0
0
8
8
0
8
0
0
0
8
0
8
% P
% Gln:
8
8
8
50
8
8
0
8
0
8
0
8
8
0
0
% Q
% Arg:
0
8
0
0
15
0
0
8
0
8
15
0
0
8
15
% R
% Ser:
22
0
8
0
22
50
0
0
8
8
0
15
0
29
8
% S
% Thr:
15
0
15
0
8
0
15
43
8
0
8
8
0
8
0
% T
% Val:
0
8
0
8
8
0
0
15
36
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _