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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
29.39
Human Site:
Y465
Identified Species:
49.74
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
Y465
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
Y465
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S515
A
C
H
Q
L
S
L
S
L
V
P
Q
G
L
L
Dog
Lupus familis
XP_547295
1021
115999
Y502
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
Y464
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Rat
Rattus norvegicus
O08874
985
112050
Y466
Q
R
H
G
M
A
L
Y
L
E
P
Q
G
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
R502
E
R
H
G
L
N
L
R
L
E
P
Q
G
M
F
Chicken
Gallus gallus
XP_422357
1013
114806
Y491
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
Y460
Q
R
H
G
M
C
L
Y
L
E
P
Q
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
R156
F
V
V
H
S
Y
K
R
F
T
F
C
D
H
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
E229
G
N
K
A
D
A
V
E
E
L
G
K
E
I
Q
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
I321
K
L
R
R
Q
R
K
I
F
P
K
H
K
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
P600
P
R
K
H
D
K
T
P
S
P
Q
K
V
G
R
Red Bread Mold
Neurospora crassa
P87253
1142
127954
H570
T
A
H
A
Q
C
V
H
L
V
P
D
F
C
G
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
46.6
100
N.A.
100
93.3
N.A.
60
100
N.A.
100
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
53.3
100
N.A.
100
93.3
N.A.
73.3
100
N.A.
100
N.A.
0
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
0
15
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
50
0
0
0
0
0
8
0
8
8
% C
% Asp:
0
0
0
0
15
0
0
0
0
0
0
8
8
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
8
58
0
0
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
15
0
8
0
8
0
8
% F
% Gly:
8
0
0
58
0
0
0
0
0
0
8
0
65
15
8
% G
% His:
0
0
72
15
0
0
0
8
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
8
0
15
0
0
8
15
0
0
0
8
15
8
0
8
% K
% Leu:
0
8
0
0
15
0
65
0
72
8
0
0
0
8
58
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
0
15
72
0
0
0
0
% P
% Gln:
50
0
0
8
15
0
0
0
0
0
8
65
0
0
8
% Q
% Arg:
0
65
8
8
0
8
0
15
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
8
8
0
8
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
8
0
0
0
50
0
% T
% Val:
0
8
8
0
0
0
15
0
0
15
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _