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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDB1 All Species: 39.7
Human Site: S386 Identified Species: 62.38
UniProt: Q16531 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16531 NP_001914.3 1140 126968 S386 S G A F K E G S L R I I R N G
Chimpanzee Pan troglodytes XP_508472 1140 126946 S386 S G A F K E G S L R I I R N G
Rhesus Macaque Macaca mulatta XP_001082958 1197 132796 S386 S G A F K E G S L R I I R N G
Dog Lupus familis XP_533275 1140 126935 S386 S G A F K E G S L R I I R N G
Cat Felis silvestris
Mouse Mus musculus Q3U1J4 1140 126834 S386 S G A F K E G S L R I I R N G
Rat Rattus norvegicus Q9ESW0 1140 126843 S386 S G A F K E G S L R I I R N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q805F9 1140 126936 S386 S G A F K E G S L R I I R N G
Frog Xenopus laevis Q6P6Z0 1140 126814 S386 S G A F K E G S L R I I R N G
Zebra Danio Brachydanio rerio NP_956920 897 99217 T177 L Y G C Q A P T V C F I Y Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYZ5 1140 126027 L385 G S F K D G S L R I I R I G I
Honey Bee Apis mellifera XP_396048 1138 126198 G385 C S G A F K E G S L R I I R N
Nematode Worm Caenorhab. elegans Q21554 1134 125700 S380 T G A D K D G S L R V I R N G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002300334 1088 121333 L342 K G T Y V E V L D R Y V N L G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0V3 1088 121288 L342 K G S Y V E V L E R Y I N L G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYR4 1209 134021 T453 C G N G A R S T F R M L K H G
Conservation
Percent
Protein Identity: 100 98.3 93.7 99.9 N.A. 99.6 98.9 N.A. N.A. 97.1 93.4 71.4 N.A. 60.9 68.5 37.9 N.A.
Protein Similarity: 100 98.7 94.6 99.9 N.A. 99.7 99.5 N.A. N.A. 98.5 96.2 75.3 N.A. 76.4 81.9 61.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 6.6 N.A. 6.6 6.6 73.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 26.6 N.A. 6.6 13.3 93.3 N.A.
Percent
Protein Identity: 53.7 N.A. N.A. 53.6 N.A. 21.6
Protein Similarity: 70.7 N.A. N.A. 70.9 N.A. 42.1
P-Site Identity: 26.6 N.A. N.A. 33.3 N.A. 20
P-Site Similarity: 40 N.A. N.A. 46.6 N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 60 7 7 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 14 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 0 7 7 7 0 0 7 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 67 7 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 7 54 7 0 0 0 7 0 7 0 0 0 0 % F
% Gly: 7 80 14 7 0 7 60 7 0 0 0 0 0 7 80 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 60 80 14 0 7 % I
% Lys: 14 0 0 7 60 7 0 0 0 0 0 0 7 0 0 % K
% Leu: 7 0 0 0 0 0 0 20 60 7 0 7 0 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 14 60 7 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 7 0 0 7 80 7 7 60 7 0 % R
% Ser: 54 14 7 0 0 0 14 60 7 0 0 0 0 0 0 % S
% Thr: 7 0 7 0 0 0 0 14 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 14 0 14 0 7 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 14 0 0 0 0 0 0 14 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _