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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB1
All Species:
33.64
Human Site:
S549
Identified Species:
52.86
UniProt:
Q16531
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16531
NP_001914.3
1140
126968
S549
D
I
T
P
L
G
D
S
N
G
L
S
P
L
C
Chimpanzee
Pan troglodytes
XP_508472
1140
126946
S549
D
I
T
P
L
G
D
S
N
G
L
S
P
L
C
Rhesus Macaque
Macaca mulatta
XP_001082958
1197
132796
S549
D
I
T
P
L
G
D
S
N
G
L
S
P
L
C
Dog
Lupus familis
XP_533275
1140
126935
S549
D
I
T
P
L
G
D
S
N
G
L
S
P
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1J4
1140
126834
S549
D
I
T
P
L
G
D
S
N
G
L
S
P
L
C
Rat
Rattus norvegicus
Q9ESW0
1140
126843
S549
D
V
T
P
L
G
D
S
N
G
L
S
P
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q805F9
1140
126936
T549
D
I
T
P
L
G
D
T
N
G
M
S
P
L
C
Frog
Xenopus laevis
Q6P6Z0
1140
126814
N549
D
V
T
P
L
G
G
N
D
T
L
S
S
L
C
Zebra Danio
Brachydanio rerio
NP_956920
897
99217
S340
L
V
K
L
N
V
D
S
N
D
Q
G
S
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XYZ5
1140
126027
T548
D
I
T
P
L
D
E
T
Q
K
K
S
D
L
V
Honey Bee
Apis mellifera
XP_396048
1138
126198
N548
D
I
S
P
L
D
G
N
T
E
A
K
I
A
A
Nematode Worm
Caenorhab. elegans
Q21554
1134
125700
D543
E
N
E
I
A
C
L
D
L
S
N
E
G
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300334
1088
121333
T505
A
T
Q
V
L
L
A
T
G
G
G
H
L
V
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0V3
1088
121288
T505
A
S
Q
V
L
L
A
T
G
G
G
H
L
V
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
G616
S
V
G
Q
V
P
E
G
L
K
R
S
S
F
L
Conservation
Percent
Protein Identity:
100
98.3
93.7
99.9
N.A.
99.6
98.9
N.A.
N.A.
97.1
93.4
71.4
N.A.
60.9
68.5
37.9
N.A.
Protein Similarity:
100
98.7
94.6
99.9
N.A.
99.7
99.5
N.A.
N.A.
98.5
96.2
75.3
N.A.
76.4
81.9
61.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
86.6
60
20
N.A.
46.6
26.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
80
26.6
N.A.
60
40
6.6
N.A.
Percent
Protein Identity:
53.7
N.A.
N.A.
53.6
N.A.
21.6
Protein Similarity:
70.7
N.A.
N.A.
70.9
N.A.
42.1
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
14
0
0
0
7
0
0
7
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
54
% C
% Asp:
67
0
0
0
0
14
54
7
7
7
0
0
7
7
7
% D
% Glu:
7
0
7
0
0
0
14
0
0
7
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
7
0
0
54
14
7
14
60
14
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
0
54
0
7
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
0
14
7
7
0
0
0
% K
% Leu:
7
0
0
7
80
14
7
0
14
0
47
0
14
60
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
14
54
0
7
0
0
0
0
% N
% Pro:
0
0
0
67
0
7
0
0
0
0
0
0
47
0
0
% P
% Gln:
0
0
14
7
0
0
0
0
7
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
7
7
0
0
0
0
47
0
7
0
67
20
0
0
% S
% Thr:
0
7
60
0
0
0
0
27
7
7
0
0
0
0
0
% T
% Val:
0
27
0
14
7
7
0
0
0
0
0
0
0
14
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _