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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDB1 All Species: 30.91
Human Site: S774 Identified Species: 48.57
UniProt: Q16531 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16531 NP_001914.3 1140 126968 S774 S S K L F S S S T A P H E T S
Chimpanzee Pan troglodytes XP_508472 1140 126946 S774 S S K L F S S S T A P H E T S
Rhesus Macaque Macaca mulatta XP_001082958 1197 132796 S774 S S K L F S S S T A P H E T S
Dog Lupus familis XP_533275 1140 126935 S774 S S K L F S S S T A P H E T S
Cat Felis silvestris
Mouse Mus musculus Q3U1J4 1140 126834 S774 S S K L F S S S T A P H E T S
Rat Rattus norvegicus Q9ESW0 1140 126843 S774 S S K L F S S S A A P H E T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q805F9 1140 126936 S774 T S K L F S S S T A P H E T S
Frog Xenopus laevis Q6P6Z0 1140 126814 S774 C S K L F S G S T S P H E T S
Zebra Danio Brachydanio rerio NP_956920 897 99217 D563 C A V G L W T D I S A R L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYZ5 1140 126027 G773 N F L P K P G G G N S T A A N
Honey Bee Apis mellifera XP_396048 1138 126198 P772 H I A S Y N K P T G H T A S D
Nematode Worm Caenorhab. elegans Q21554 1134 125700 P776 R A D M D E S P P N T T S S F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002300334 1088 121333 C730 Q S R T F S I C S M K N Q S N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0V3 1088 121288 C730 Q T R T F G I C S L G N Q S N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYR4 1209 134021 P846 P P E D F G Y P R A K G R W A
Conservation
Percent
Protein Identity: 100 98.3 93.7 99.9 N.A. 99.6 98.9 N.A. N.A. 97.1 93.4 71.4 N.A. 60.9 68.5 37.9 N.A.
Protein Similarity: 100 98.7 94.6 99.9 N.A. 99.7 99.5 N.A. N.A. 98.5 96.2 75.3 N.A. 76.4 81.9 61.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 93.3 80 0 N.A. 0 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 100 86.6 20 N.A. 13.3 26.6 26.6 N.A.
Percent
Protein Identity: 53.7 N.A. N.A. 53.6 N.A. 21.6
Protein Similarity: 70.7 N.A. N.A. 70.9 N.A. 42.1
P-Site Identity: 20 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 60 N.A. N.A. 53.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 0 0 0 0 0 7 54 7 0 14 7 7 % A
% Cys: 14 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 7 0 0 7 0 0 0 0 0 0 7 % D
% Glu: 0 0 7 0 0 7 0 0 0 0 0 0 54 0 0 % E
% Phe: 0 7 0 0 74 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 7 0 14 14 7 7 7 7 7 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 7 54 0 0 0 % H
% Ile: 0 7 0 0 0 0 14 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 54 0 7 0 7 0 0 0 14 0 0 0 7 % K
% Leu: 0 0 7 54 7 0 0 0 0 7 0 0 7 7 0 % L
% Met: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 0 0 0 14 0 14 0 0 20 % N
% Pro: 7 7 0 7 0 7 0 20 7 0 54 0 0 0 0 % P
% Gln: 14 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % Q
% Arg: 7 0 14 0 0 0 0 0 7 0 0 7 7 0 0 % R
% Ser: 40 60 0 7 0 60 54 54 14 14 7 0 7 27 54 % S
% Thr: 7 7 0 14 0 0 7 0 54 0 7 20 0 54 0 % T
% Val: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _