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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDB1 All Species: 40.91
Human Site: T192 Identified Species: 64.29
UniProt: Q16531 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16531 NP_001914.3 1140 126968 T192 P Q G R H V K T Y E V S L R E
Chimpanzee Pan troglodytes XP_508472 1140 126946 T192 P Q G R H V K T Y E V S L R E
Rhesus Macaque Macaca mulatta XP_001082958 1197 132796 T192 P Q G R H V K T Y E V S L R E
Dog Lupus familis XP_533275 1140 126935 T192 P Q G R H V K T Y E V S L R E
Cat Felis silvestris
Mouse Mus musculus Q3U1J4 1140 126834 T192 P Q G R H V K T Y E V S L R E
Rat Rattus norvegicus Q9ESW0 1140 126843 T192 P Q G R H V K T Y E V S L R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q805F9 1140 126936 T192 P Q G R H V K T Y E V S L R E
Frog Xenopus laevis Q6P6Z0 1140 126814 T192 P Q G R H V K T Y E V S L R E
Zebra Danio Brachydanio rerio NP_956920 897 99217 A9 S Y N Y V V T A Q K P T A V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYZ5 1140 126027 S192 S D G R H V K S H E I N L R D
Honey Bee Apis mellifera XP_396048 1138 126198 T192 I N G R H V K T H E I S L R D
Nematode Worm Caenorhab. elegans Q21554 1134 125700 F188 D H G K H L Q F S D L N M H D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002300334 1088 121333 S173 I K F L H G C S K P T I V V L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0V3 1088 121288 C172 D I K F L F G C A K P T I A V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYR4 1209 134021 E209 P T G Q A R E E V E T Q L V Y
Conservation
Percent
Protein Identity: 100 98.3 93.7 99.9 N.A. 99.6 98.9 N.A. N.A. 97.1 93.4 71.4 N.A. 60.9 68.5 37.9 N.A.
Protein Similarity: 100 98.7 94.6 99.9 N.A. 99.7 99.5 N.A. N.A. 98.5 96.2 75.3 N.A. 76.4 81.9 61.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 6.6 N.A. 53.3 66.6 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 20 N.A. 86.6 86.6 66.6 N.A.
Percent
Protein Identity: 53.7 N.A. N.A. 53.6 N.A. 21.6
Protein Similarity: 70.7 N.A. N.A. 70.9 N.A. 42.1
P-Site Identity: 6.6 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 7 7 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 14 7 0 0 0 0 0 0 0 7 0 0 0 0 20 % D
% Glu: 0 0 0 0 0 0 7 7 0 74 0 0 0 0 54 % E
% Phe: 0 0 7 7 0 7 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 80 0 0 7 7 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 80 0 0 0 14 0 0 0 0 7 0 % H
% Ile: 14 7 0 0 0 0 0 0 0 0 14 7 7 0 0 % I
% Lys: 0 7 7 7 0 0 67 0 7 14 0 0 0 0 0 % K
% Leu: 0 0 0 7 7 7 0 0 0 0 7 0 74 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 0 0 0 14 0 0 7 % N
% Pro: 60 0 0 0 0 0 0 0 0 7 14 0 0 0 0 % P
% Gln: 0 54 0 7 0 0 7 0 7 0 0 7 0 0 0 % Q
% Arg: 0 0 0 67 0 7 0 0 0 0 0 0 0 67 0 % R
% Ser: 14 0 0 0 0 0 0 14 7 0 0 60 0 0 0 % S
% Thr: 0 7 0 0 0 0 7 60 0 0 14 14 0 0 0 % T
% Val: 0 0 0 0 7 74 0 0 7 0 54 0 7 20 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 0 0 54 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _