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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB1
All Species:
32.73
Human Site:
T424
Identified Species:
51.43
UniProt:
Q16531
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16531
NP_001914.3
1140
126968
T424
P
N
R
E
T
D
D
T
L
V
L
S
F
V
G
Chimpanzee
Pan troglodytes
XP_508472
1140
126946
T424
P
N
R
E
T
D
D
T
L
V
L
S
F
V
G
Rhesus Macaque
Macaca mulatta
XP_001082958
1197
132796
T424
P
N
R
E
T
D
D
T
L
V
L
S
F
V
G
Dog
Lupus familis
XP_533275
1140
126935
T424
P
N
R
E
T
D
D
T
L
V
L
S
F
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1J4
1140
126834
T424
P
G
R
E
T
D
D
T
L
V
L
S
F
V
G
Rat
Rattus norvegicus
Q9ESW0
1140
126843
T424
P
N
R
E
T
D
D
T
L
V
L
S
F
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q805F9
1140
126936
M424
S
H
R
E
M
D
N
M
L
V
L
S
F
V
G
Frog
Xenopus laevis
Q6P6Z0
1140
126814
T424
A
D
R
D
T
D
D
T
L
V
L
S
F
V
G
Zebra Danio
Brachydanio rerio
NP_956920
897
99217
E215
K
Q
E
N
V
E
A
E
A
S
M
V
I
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XYZ5
1140
126027
T423
D
E
S
P
Y
E
N
T
L
V
L
A
F
V
G
Honey Bee
Apis mellifera
XP_396048
1138
126198
T423
G
G
G
N
F
D
N
T
L
V
L
S
F
V
G
Nematode Worm
Caenorhab. elegans
Q21554
1134
125700
I418
S
N
A
D
N
Y
V
I
V
S
L
S
D
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300334
1088
121333
R380
A
Y
K
D
G
S
L
R
I
V
R
N
G
I
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0V3
1088
121288
R380
A
F
K
D
G
S
L
R
V
V
R
N
G
I
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
A491
T
K
Y
D
Q
Y
D
A
Y
I
V
L
S
F
T
Conservation
Percent
Protein Identity:
100
98.3
93.7
99.9
N.A.
99.6
98.9
N.A.
N.A.
97.1
93.4
71.4
N.A.
60.9
68.5
37.9
N.A.
Protein Similarity:
100
98.7
94.6
99.9
N.A.
99.7
99.5
N.A.
N.A.
98.5
96.2
75.3
N.A.
76.4
81.9
61.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
66.6
80
0
N.A.
46.6
60
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
N.A.
80
93.3
13.3
N.A.
66.6
66.6
33.3
N.A.
Percent
Protein Identity:
53.7
N.A.
N.A.
53.6
N.A.
21.6
Protein Similarity:
70.7
N.A.
N.A.
70.9
N.A.
42.1
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
46.6
N.A.
N.A.
46.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
7
0
0
0
7
7
7
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
34
0
60
54
0
0
0
0
0
7
0
0
% D
% Glu:
0
7
7
47
0
14
0
7
0
0
0
0
0
7
0
% E
% Phe:
0
7
0
0
7
0
0
0
0
0
0
0
67
7
0
% F
% Gly:
7
14
7
0
14
0
0
0
0
0
0
0
14
0
80
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
7
7
0
0
7
14
0
% I
% Lys:
7
7
14
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
14
0
67
0
74
7
0
0
0
% L
% Met:
0
0
0
0
7
0
0
7
0
0
7
0
0
0
0
% M
% Asn:
0
40
0
14
7
0
20
0
0
0
0
14
0
0
0
% N
% Pro:
40
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
54
0
0
0
0
14
0
0
14
0
0
0
0
% R
% Ser:
14
0
7
0
0
14
0
0
0
14
0
67
7
0
0
% S
% Thr:
7
0
0
0
47
0
0
60
0
0
0
0
0
0
14
% T
% Val:
0
0
0
0
7
0
7
0
14
80
7
7
0
67
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
7
14
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _