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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDB1
All Species:
40.61
Human Site:
T646
Identified Species:
63.81
UniProt:
Q16531
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16531
NP_001914.3
1140
126968
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Chimpanzee
Pan troglodytes
XP_508472
1140
126946
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Rhesus Macaque
Macaca mulatta
XP_001082958
1197
132796
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Dog
Lupus familis
XP_533275
1140
126935
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3U1J4
1140
126834
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Rat
Rattus norvegicus
Q9ESW0
1140
126843
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q805F9
1140
126936
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Frog
Xenopus laevis
Q6P6Z0
1140
126814
T646
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Zebra Danio
Brachydanio rerio
NP_956920
897
99217
V435
S
F
V
G
Q
T
R
V
L
M
L
S
G
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XYZ5
1140
126027
T645
R
T
F
R
S
L
S
T
T
N
V
F
A
C
S
Honey Bee
Apis mellifera
XP_396048
1138
126198
T644
R
T
F
R
S
L
F
T
T
N
V
F
A
C
S
Nematode Worm
Caenorhab. elegans
Q21554
1134
125700
R648
H
R
V
R
N
K
N
R
Q
H
L
F
V
C
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300334
1088
121333
D602
Y
L
L
C
A
L
G
D
G
H
L
L
N
F
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0V3
1088
121288
D602
Y
L
L
C
A
L
G
D
G
H
L
L
N
F
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
Q718
F
Q
V
S
V
Q
D
Q
P
C
V
L
A
L
S
Conservation
Percent
Protein Identity:
100
98.3
93.7
99.9
N.A.
99.6
98.9
N.A.
N.A.
97.1
93.4
71.4
N.A.
60.9
68.5
37.9
N.A.
Protein Similarity:
100
98.7
94.6
99.9
N.A.
99.7
99.5
N.A.
N.A.
98.5
96.2
75.3
N.A.
76.4
81.9
61.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
0
N.A.
100
93.3
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
6.6
N.A.
100
93.3
53.3
N.A.
Percent
Protein Identity:
53.7
N.A.
N.A.
53.6
N.A.
21.6
Protein Similarity:
70.7
N.A.
N.A.
70.9
N.A.
42.1
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
0
0
0
0
0
74
0
0
% A
% Cys:
0
0
0
14
0
0
0
0
0
7
0
0
0
74
0
% C
% Asp:
0
0
0
0
0
0
7
14
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% E
% Phe:
7
7
67
0
0
0
7
0
0
0
0
74
0
14
0
% F
% Gly:
0
0
0
7
0
0
14
0
14
0
0
0
7
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
14
14
0
0
80
0
0
7
0
27
20
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
67
0
0
14
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
7
7
0
7
7
0
0
0
0
0
7
% Q
% Arg:
67
7
0
74
0
0
7
7
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
7
67
0
60
0
0
0
0
7
0
0
80
% S
% Thr:
0
67
0
0
0
7
0
67
67
0
0
0
0
0
0
% T
% Val:
0
0
20
0
7
0
0
7
0
0
74
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _