Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDB1 All Species: 26.67
Human Site: T745 Identified Species: 41.9
UniProt: Q16531 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16531 NP_001914.3 1140 126968 T745 S R I E V Q D T S G G T T A L
Chimpanzee Pan troglodytes XP_508472 1140 126946 T745 S R I E V Q D T S G G T T A L
Rhesus Macaque Macaca mulatta XP_001082958 1197 132796 T745 S R I E V Q D T S G G T T A L
Dog Lupus familis XP_533275 1140 126935 T745 S R I E V Q D T S G G T T A L
Cat Felis silvestris
Mouse Mus musculus Q3U1J4 1140 126834 S745 S R I E V Q D S S G G T T A L
Rat Rattus norvegicus Q9ESW0 1140 126843 T745 T R I E V Q D T S G G T T A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q805F9 1140 126936 A745 S R I E V Q D A S G G T T A L
Frog Xenopus laevis Q6P6Z0 1140 126814 A745 S R I E V Q D A S G G S S P L
Zebra Danio Brachydanio rerio NP_956920 897 99217 M534 K Q I S S T E M E H E V A C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYZ5 1140 126027 R744 L R I D V H G R G G A K P L R
Honey Bee Apis mellifera XP_396048 1138 126198 S743 M R V D I Q D S S G V S I V R
Nematode Worm Caenorhab. elegans Q21554 1134 125700 E747 N R T E S K A E R V F A S K N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002300334 1088 121333 I701 S I G T I D D I Q K L H I R S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0V3 1088 121288 I701 T I G T I D D I Q K L H I R T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RYR4 1209 134021 T817 T I E S D N N T L P P E L R A
Conservation
Percent
Protein Identity: 100 98.3 93.7 99.9 N.A. 99.6 98.9 N.A. N.A. 97.1 93.4 71.4 N.A. 60.9 68.5 37.9 N.A.
Protein Similarity: 100 98.7 94.6 99.9 N.A. 99.7 99.5 N.A. N.A. 98.5 96.2 75.3 N.A. 76.4 81.9 61.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 73.3 13.3 N.A. 26.6 33.3 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 26.6 N.A. 33.3 66.6 33.3 N.A.
Percent
Protein Identity: 53.7 N.A. N.A. 53.6 N.A. 21.6
Protein Similarity: 70.7 N.A. N.A. 70.9 N.A. 42.1
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 20 N.A. N.A. 20 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 14 0 0 7 7 7 47 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 14 7 14 74 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 60 0 0 7 7 7 0 7 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 14 0 0 0 7 0 7 67 54 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 7 0 14 0 0 0 % H
% Ile: 0 20 67 0 20 0 0 14 0 0 0 0 20 0 0 % I
% Lys: 7 0 0 0 0 7 0 0 0 14 0 7 0 7 0 % K
% Leu: 7 0 0 0 0 0 0 0 7 0 14 0 7 7 60 % L
% Met: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 7 0 7 7 0 % P
% Gln: 0 7 0 0 0 60 0 0 14 0 0 0 0 0 0 % Q
% Arg: 0 74 0 0 0 0 0 7 7 0 0 0 0 20 14 % R
% Ser: 54 0 0 14 14 0 0 14 60 0 0 14 14 0 7 % S
% Thr: 20 0 7 14 0 7 0 40 0 0 0 47 47 0 7 % T
% Val: 0 0 7 0 60 0 0 0 0 7 7 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _